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As any detective can tell you, investigating missing property or deaths is comparatively easy compared to elusive missing people. However in New York City, there is a special unit of the FBI that is designed to find them. Using the vast resources of their bureau, the team, lead by Agent Jack Malone, race against time in the tight 72 hour window after a disappearance while hope for a recovery is still typically possible.

About Jane Timoney, an iconoclastic female detective who has to make her bones in a tough New York precinct that is dominated by men.

Former CIA operative is lured back to his old life when the NYPD needs his help to stop a serial killer. Dr. Dylan Reinhart (Alan Cumming) is a gifted author and university professor living a quiet life teaching psychopathic behavior to packed classes of adoring students. But when top NYPD detective Lizzie Needham (Bojana Novakovic) appeals to him to help her catch a serial murderer who is using Dylan's first book as a tutorial, Dylan is compelled by the case, comes out of retirement and taps into his old skill set. Though Dylan and Lizzie initially clash, when it comes to catching killers, they realize they will make an ideal team if they both trust their instincts. Based on the James Patterson book.

This show centers on the NYPD's Major Case Squad (and the offbeat, Sherlock Holmes-like Detective Robert Goren) in its efforts to stop the worst criminal offenders in New York. It also puts a new twist to the "Law & Order" formula: now, in each episode, we see the crimes as they are planned and committed.

In the Los Angeles office of the Federal Bureau of Investigation, Special Agent Don Eppes and his team investigate critical and baffling crimes with a special edge. That advantage is Don's brother, Charles Eppes, a brilliant universalist mathematician who uses the science of mathematics with its complex equations to ferret out the most tricky criminals. With this team, the forces of evil learn their number is up.

Lilly Rush is a Philadelphia police detective working for the department's homicide squad and being assigned "cold cases": crimes that were committed many years before and have not been solved. Lilly must try to re-think the crime scenes and interview other people involved with the victims to find a link to solving the cases.

On the streets of San Francisco a team of the Federal Bureau of Investigation's Behavioral Analysis Unit use profiling to catch some of the most horrific serial killers and unidentifiable subjects.

Carrie Wells, a former police detective, has a rare ability to remember virtually everything she experiences including detailed visual recall. She returns to police work and uses her ability to solve crimes.

When you first saw him, Lieutenant Columbo looked like a bum that just came off the street. He had a bumbling demeanor, was overly polite and seemed to chomp on the same short cigar on a daily basis. However, beneath all that comical exterior was probably the most dogged investigator in the Los Angeles Police Department. Columbo was often called on to investigate high profile murders that involved the rich and famous. The culprits were often amused by him, and just as they thought they were going to get away with murder, Columbo would find a way to trap them or find enough evidence to make them confess.

Brilliant, but socially inept, forensic anthropologist Dr. Temperence Brennan works at the Jeffersonian Institute in Washington DC. After consulting for him on a FBI case, she is approached by cocky yet charming Former Army Ranger turned Special Agent, Seeley Booth to help the Bureau solve crimes by identifying human remains that are too far gone for standard FBI forensic investigations. Brennan's empirical, literal view of the world causes friction with Booths emotive, instinctive attitude creating a volatile relationship. However as their case load increases the symbiotic partnership produces results and with the support of Brennan's Squint Squad, murderers, past and present should be on the look out.

The best private pathologist in Miami, Dr. Beaumont Rosewood, Jr., whose rare heart condition that could kill him at any moment fuels his lust for life, gives a second opinion when friends or family of the deceased are not satisfied with official police findings. His state-of-the-art laboratory equipment, Sherlock Holmes-like powers of deduction and quick wit are his main tools. He also relies and depends on his trusty assistants and cute couple, Pippy and TMI, and works with no-nonsense detective Annalise Villa, who doesn't always go strictly by the book, to see the case to its conclusion.

Richard "Rick" Castle is a millionaire playboy who recently killed off his main character when a serial killer starts killing people like he does in his books. He teams up with New York police detective Kate Beckett to solve the case. He finds inspiration in Detective Beckett and starts shadowing her for his next book.

Dr. Daniel Pierce is an eccentric neuropsychiatrist who uses his unique outlook to help the federal government solve complex criminal cases.

Deputy Police Chief Brenda Leigh Johnson, formerly Atlanta police officer and CIA-trained interrogator, is given the opportunity to run her own division of elite officers of the Los Angeles Police Department. Her unusual procedure for obtaining confessions, blatant disregard for politics, and southern accent make her a marked woman. However, with all the bluster and bravado, she still maintains her title, The Closer.

Dr. Mark Sloan is a doctor at Community General Hospital, and he is a consultant for the police department. His son Steve Sloan is a detective for the department. He and his father, along with emergency room resident Dr. Jesse Travis and Dr. Amanda Bentley, who is the pathologist at the hospital help to solve some very strange murder cases in Diagnosis Murder.

Detective Jane Rizzoli and Chief Medical Examiner Dr. Maura Isles team up to solve crimes in Boston.

A homicide detective, a medical examiner, a newspaper reporter and a young assistant district attorney work together to solve homicide investigations.

After the unsolved murder of his wife, Trudy, Adrian Monk develops obsessive-compulsive disorder, which includes his terror of germs and contamination. His condition costs him his job as a prominent homicide detective in the San Francisco Police Department, but he continues to solve crimes with the help of his assistant and his former boss.