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Six New Yorkers juggle love, friendship, and the keenly challenging specter of adulthood. Sam Wexler is a struggling writer who's having a particularly bad day. When a young boy gets separated from his family on the subway, Sam makes the questionable decision to bring the child back to his apartment and thus begins a rewarding, yet complicated, friendship. Sam's life revolves around his friends-Annie, whose self-image keeps her from commitment; Charlie and Mary Catherine, a couple whose possible move to Los Angeles tests their relationship; and Mississippi, a cabaret singer who catches Sam's eye.

Two sisters, 11-year-old Amanda and 16-year-old Laurel, run away from their different foster parents and sleep in model homes and wherever else they can. But when Laurel becomes pregnant. they realize they can't handle this crisis on their own. With nowhere else to turn, they decide to kidnap Elaine, a clerk in a baby-supply store. But Elaine seems to need Manny and Lo just as much as they need her.

Sheltered by his grandparents, Luke, a young man with autism, is thrust into a world that doesn't expect anything from him. But Luke is on a quest for a job and true love. And he isn't taking no for an answer.

Soon after moving in, Beth, a brainy, beautiful writer damaged from a past relationship encounters Adam, the handsome, but odd, fellow in the downstairs apartment whose awkwardness is perplexing. Beth and Adam's ultimate connection leads to a tricky relationship that exemplifies something universal: truly reaching another person means bravely stretching into uncomfortable territory and the resulting shake-up can be liberating.

Successful Carolinian George Johnsten meets Chicago art gallery owner Madeleine at an electoral benefit art auction- love at first sight. Madeleine decides to meet a Southern original artist, so George seizes the opportunity to come along and present her to his North Carolina parents Eugene and Peg, drop-out brother Johny and his high-pregnant wife Ashley. Confronting the outsider soon opens a can of worms as emotions revive or emerge, like admiration and jealousy.

The relationship between two brothers, a father trying to connect with his sons and the young woman who gets between the three of them. The story begins when Caleb Sinclaire reluctantly picks up his brother Peter at college and brings him and his new girlfriend Emma home for the Thanksgiving holiday. Caleb, who recently broke up with his long-time girlfriend and is wary of relationships, warns Peter that Emma will end up hurting him, but he can't stop himself from being drawn to her. As Caleb's infatuation with Emma grows, he must decide whether to act on his feelings or protect his brother's first love.

About a recent college grad who returns home while she tries to figure out what to do with her life.

A family weekend is fraught with emotional landmines for mercurial and sensitive Lynn (Barkin) as she arrives at her parents' Annapolis estate for the marriage of her estranged eldest son Dylan (Michael Nardelli), accompanied by her three younger children (Ezra Miller, Kate Bosworth, Daniel Yelsky). Lynn's hopes for a joyful reunion are crushed as her wry but troubled middle son Elliot (Ezra Miller) lobs verbal grenades at his mother and her relatives while daughter Alice (Kate Bosworth), a fights valiantly to keep her longtime demons under control. The weekend quickly unravels as Lynn demands to be heard by her aloof, disdainful mother (Ellen Burstyn), ailing, distant father (George Kennedy) and ever-judgmental sisters (Siobhan Fallon, Diana Scarwid), but most especially by her ex-husband Paul (Thomas Hayden Church) and his hot-tempered second wife Patty (Demi Moore). Confronted with the deeply painful, half-buried truths that have given rise to the family's primal web ofresentments and recriminations, Lynn struggles to maintain her equilibrium as her best attempts at reconciliation veer quickly off-course.

They're in their 20s. He works in a video store; he's eager, chatty, sleeps in his car. She rents adult films, looks disheveled, rarely speaks. He chats her up, she brushes him off. He takes her address from store records and contrives to run into her. He rings her doorbell; she tells him to go away. He invents a story of a great-aunt who lives in the building and fakes her death to get the girl to let him in her apartment but holds a butcher knife between them. So it goes and he is no longer living in his car. He presses for a relationship; she ignores him, insults him, or yells. He's persistent, inviting her to get out of the apartment, cooking, washing her hair. Both have demons and, as their stories become more clear, his addictive personality and her sex nausea may be on a collision course.

Something's wrong at the Rileys. Married nearly 30 years, Doug and Lois rarely talk. She doesn't leave their Indianapolis home, and she's ordered a gravestone with their names and birth years on it. He has a long-time Thursday night mistress whom he invites to go with him to a plumbing supply conference in New Orleans. Once there, Doug calls Lois to say he's staying for a while. What's he leaving behind and what's he looking for in New Orleans? And Lois, can she break out?

Do we ever get what we want? Brian sells mattresses in a warehouse store. His father and older brothers have material success; he wants a child. He's applied to adopt a baby from China. A man who appears homeless seems to be stalking Brian with violent intent. He meets Happy, the daughter of a rich, quirky customer. She doesn't stick to anything, but she and Brian hit it off, except for her vomiting when she learns about his adoption idea. He wants her to meet his family, and there's a call about the adoption. What will Happy do?

In a small Southern American town, Paul, who is known for having sexual relations with every girl in town, falls in love with his best friend's younger sister who is a virgin. Paul must try to prove to everyone that this time he is in love rather than in lust.

Nora Wilder is freaking out. Everyone around her is either in a relationship, married, or has children. Nora is in her thirties, alone with job she's outgrown and a mother who constantly reminds her of it all. Not to mention her best friend Audrey's "perfect marriage". But after a series of disastrous dates, Nora unexpectedly meets Julien, a quirky Frenchman who opens her eyes to a lot more than love.

Rachel is a quick-witted and lovable stay-at-home mom. Frustrated with the realities of preschool auctions, a lackluster sex life and career that's gone kaput, Rachel visits a strip club to spice up her marriage and meets McKenna, a stripper she adopts as her live-in nanny.

A series of overlapping stories about four suburban families dealing with different maladies. Esther Gold's life is consumed by caring for her comatose son; Jim Train is sent into a tailspin when he's passed over for a promotion; Annette Jennings' family is struggling in the wake of her divorce; Helen Christianson is determined to shake up her mundane life.

T.J., a high school freshman, lost his mother two months before in a car accident: his father pops pills and sits on the couch; his grandmother holds things together, chatting and cooking. T.J. wants the car back from the salvage yard where the owner's son is a bully. By happenstance, Hesher, a foul-mouthed squatter, moves in with T.J's family. T.J. also meets Nicole, a grocery clerk near poverty who helps him once. Hesher involves T.J. in crime, the bully is omnipresent, mom's car is slipping away, dad has checked out, T.J. watches Nicole at work, and his grandma invites him to join her morning walk: the odds are long that T.J. can assemble a family to help him thrive.

Actress Reese Holden has been offered a small fortune by a book editor if she can secure for publication the love letters that her father, a reclusive novelist, wrote to her mother, who has since passed away. Returning to Michigan, Reese finds that an ex-grad student and a would-be musician have moved in with her father, who cares more about his new friends than he does about his own health and well-being.

Henry Roth: obsessive-compulsive, somewhat misanthropic, a writer of children's books. His illustrator and only friend, Rudy, dies after a fabulously successful collaboration on "Marty, the Beaver." Henry is under contract to produce another Marty book for Christmas sales. His publisher, Arthur Planck, assigns penniless, lovelorn illustrator Lucy Reilly to work with Henry. She's sought by her ex-boyfriend Jeremy, who dumped her two years ago but shows up apologetic, having dedicated his new book to her. She and Henry go to a house on the shore to work. Will love bloom amid the rocks, or is Henry a bump on Lucy's road to Jeremy? Rudy's voice, from the grave, gives Henry counsel.