Jerome, a kid from the suburbs who loves to draw, goes to New York City's Strathmore College for his freshman year as a drawing major. Competition and petty jealousy consume faculty and students, with an end-of-first-semester best-student award held out as a grand plum. Worse, a strangler is on the loose, killing people on or next to campus. The idealistic Jerome falls in love with Audrey, a student who models for life-drawing classes and who responds to his sweetness. But he has a rival: the clean-cut, manly Jonah, also a first-year drawing student, whose primitive work draws raves and Audrey's attention. As cynicism seems to corrode everything, Jerome is desperate to win.

Middle-aged, sexually repressed Sylvia Stickles is the subject of this John Water's film, set in North Baltimore. She refuses to have sex with her husband, Vaughn Stickles, and keeps her overly-endowed daughter, Caprice, locked in her room, while she serves home detention for moral depravity charges. Sylvia, together with her mother Big Ethel, lead a group calling themselves "neuters" that promotes decency on Harford Road. When Sylvia is accidentally hit on the head by a lawnmower hanging out of a passing pick-up truck, however, her sexual behavior is changed completely from prude to prostitute. She meets the sex addicted sexual healer Ray Ray Perkins, becoming his twelfth apostle of sex in a journey of pleasure and orgasm.

What Is It? is a bewildering, unnerving, surreal, blackly comic film from the visionary mind of Crispin Glover that tells the inner and outer struggles of a young man facing villains and demons on multiple planes.

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