Astronaut Roy McBride (Brad Pitt) travels to the outer edges of the solar system to find his missing father and unravel a mystery that threatens the survival of our planet. His journey will uncover secrets that challenge the nature of human existence and our place in the cosmos.

Six astronauts aboard the space station study a sample collected from Mars that could provide evidence for extraterrestrial life on the Red Planet. The crew determines that the sample contains a large, single-celled organism - the first example of life beyond Earth. But..things aren't always what they seem. As the crew begins to conduct research, and their methods end up having unintended consequences, the life form proves more intelligent than anyone ever expected.

The spaceship, Starship Avalon, in its 120-year voyage to a distant colony planet known as the "Homestead Colony" and transporting 5,258 people has a malfunction in one of its sleep chambers. As a result one hibernation pod opens prematurely and the one person that awakes, Jim Preston (Chris Pratt) is stranded on the spaceship, still 90 years from his destination.

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