Makoto Naegi, the Ultimate Hope who defeated the Ultimate Despair, Junko Enoshima, is under suspicion of treason against the Future Foundation for harboring the Remnants of Despair who carried on her will. As top members of the Future Foundation, including Makoto's former classmates Kyoko Kirigiri, Aoi Asahina, and Yasuhiro Hagakure, are brought together to decide on Makoto's punishment, they are all imprisoned by Monokuma, the bear avatar of Junko who was thought to have been dead. Monokuma forces everyone to participate in a final killing game, in which they must try to determine a traitor amongst their ranks who will kill them in their sleep, while also trying to avoid being poisoned to death by personalised forbidden actions. Thrust into a game where no one can trust each other, Makoto's ideals of hope are pushed to their very limits.

Twenty-six years ago, in a third-year classroom of a middle school, there was a student named Misaki. As an honors student who was also good at sports, the charming boy was popular with his classmates. When he suddenly died, his classmates decided to carry on as if he was still alive until graduation. Then, in the spring of 1998, a boy named Sakakibara Kouichi transfers to that classroom, and he grows suspicious of the fearful atmosphere in that classroom. In particular, there is a beautiful, aloof girl named Mei Misaki who wears an eye-patch and is always alone drawing pictures.

Vampire queen Mina Tepesh comes out of hiding to offer peace between vampires and humans. Japan gives her a bund, where she goes to live with her people. However, extremist human and vampire groups do not want to coexist.

It's not easy to find the perfect girl, even when you're the same sex! Kanako thought attending an all-girls school would be the perfect way to meet the girl of her dreams, but after her hot new roommate turns out to be a guy in drag, and catching the eye of the most popular girl in school only brings down the wrath of all the OTHER similarly obsessed girls, she's not so sure! Complicate things with a cat-eared dorm leader, her roommate's rude-mannered maid, an identical twin sister (who attends an all-boys school of course) and WAY too many attractive girls of questionable persuasions and the question becomes whether Kanako will die from frustrated nosebleeds! (Life would be SO much easier if guys didn't literally give her the hives!) Will Kanako ever find a non-polar opposite of a compatible non-opposing polarity? Let's just say that the quest for true love will not run straight in Maria Holic.

After death, humans are either reincarnated or sent to the void. Before this happens, they arrive at the Quindecim, a bar attended by the mysterious white-haired Decim. In order to fairly judge them, he has them play a Game, wherein they reveal their true nature. Decim himself is the arbiter of who wins and who loses.

This is a shivering pure love psycho horror story of a girl named Satou Matsuzaka, who has someone she likes. She experiences a sweet feeling when she sleeps with her, and thought it must be love. Everything will be forgiven as long as she protects this feeling, even if she tricks, commits crimes, steals, or even kills, she thought.

A virgin girl named Mamori who arrives on an island must compete in battle using special powers only activated through her sexual activity with the other girls on the island.

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