The cynical and skeptical writer Mike Enslin writes books evaluating supernatural phenomena in hotels, graveyards and other haunted places, usually debunking the mystery. While writing his latest book, he travels from Los Angeles to New York to spend one night in the Dolphin Hotel's posessed room 1408, which is permanently unavailable for guests. The reluctant manager Mr. Gerald Olin objects to his request and offers an upgrade, expensive booze and finally relates the death of more than fifty guests over decades in the cursed room. However Mike threatens Mr. Olin, promising to sue the hotel, and is finally allowed to check into the room. Later in the night, he finds that guests of room 1408, once they have checked in, might never leave the room alive.

Fifteen years after a horrifying experience of abduction and prolonged torture, Lucie embarks on a bloody quest for revenge against her oppressors. Along with her childhood friend, Anna, who also suffered abuse, she quickly descends, without hope, into madness and her own delusions. Anna, left on her own begins to re-experience what Lucie did when she was only twelve years old.

In 1966, in North Bend, Oregon, the runaway Kristen is captured by the police after burning down a farmhouse and is locked in the North Bend Psychiatric Hospital. Kristen is introduced to Dr. Gerald Stringer, who uses experimental therapy. Then she meets the inmates Emily, Sarah, Zoey and Iris and the tough nurse Lundt. During the night and in the shower later, Kristen sees the ghost of a woman and she learns that she is Alice Leigh Hudson, a mysterious wicked intern that has disappeared. When Iris is ready to go home, she is attacked by the ghost of Alice in the basement and murdered. She vanishes and the inmates decide to seek Iris out. Then Sarah is abducted by the Alice and also killed; the next one is Emily. Meanwhile Kristen escapes from her room and meets Zoey, expecting to protect her. However, Zoey is kidnapped by Alice and Kristen runs to Dr. Stringer's office. She snoops his desk and finds a report with the truth about Alice.

Psychological

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