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Life really sucks for a group of gay and lesbian teenagers living in Los Angeles. Their parents kicked them out, they're broke and bored, their lovers cheat on them, they're harassed by gay-bashers. If things are going to be this way, maybe suicide isn't a bad idea; at least not in the mind of Andy, our major protagonist, who gives the film its title by describing himself as "totally fucked up."

Seventeen-year-old Anne just fell in love with Sasha, the most popular girl at her LA public high school. But when Anne tells her best friend Clifton - who has always harbored a secret crush - he does his best to get in the way.

Two attractive young lesbians, Maggie and Kim, meet in Vancouver, develop a passionate romance, and move in together. Meanwhile, Maggie's well-meaning but naive mother Lila gets divorced and decides to move to Vancouver and join the household. Soon after, Lila is befriended by Judy, a transsexual about to undergo a sex-change operation. Complications ensue as the conservative Lila learns the truth about Maggie, Judy, and their diverse group of friends.

Three girls, each about 15, deal with puberty, the onset of sexual attraction, and, for two, the pressure of virginity. Marie, who's slight and diffident, quiet and nearly expressionless, is friends with Anne, who's a bit chunky and impulsive and has decided that François will be her first love. Watching synchronized swimming, Marie is suddenly attracted to the team captain Floriane--beautiful, aloof, tall, and rumored to be a slut. François pursues her and Marie begins to hang around her; they trade favors, and an odd friendship forms. Each experiences her own first, and Marie must sort out attraction and friendship.

In the small southern town of Azalea Springs, the country club set still rules. Here, being a member of "The League" is a must, big hair is still favored by the ladies who lunch, and only hair-dressers and interior designers are supposed to be gay. The addition of an AIDS facility in Azalea Springs has The League unsettled. And the announcement that their charity work will include contact with "those people" leaves them stunned. But the real frenzy begins with a drunken comment regarding the local drinking water. Rumor has it that the water is contaminated with something that actually "turns" people gay. Mix in Brother Daniel's "Homo-No-Mo" meetings, the local newspaper, and a group of rabid homophobic picketers, and you've got a recipe for panic. Heads reel. Women weep. Mothers, hide your children! In the midst of it all, we find Alex Stratton, a young woman dealing with a distant husband, an overbearing mother, and the tedium of meaningless society chatter and endless shoe critics. Going against her husband's and her mother's wishes, Alex accepts a job at the Hospice where she is reacquainted with Grace Miller, her best friend from high school who has returned to Azalea Springs after a nasty divorce. It is here that Alex falls out of 'grace' with society when the two are caught kissing in the Hospice supply room. Mark Anderson works at the local newspaper his father owns and regularly attends Brother Daniel's Turn-or-Burn meetings. As the rumor about the water and the protesters get plenty of front page coverage, Mark finds himself becoming involved with Tomas, a Latin house painter who mistakes the ex-gay meeting for an A.A. meeting. The events that unravel as a result of these two love affairs bear witness to what happens when hysteria and homophobia take control of their lives.

Gray and Sam are brother and sister and best friends, flatmates in New York City, where she creates ad campaigns and he's a surgery intern. Their social life is too insular, so they head to a dog park so Sam can, maybe, meet a woman. He does - Charlie - a zoologist new in the city; he likes her immediately, and the feeling seems mutual. As the three of them spend time together, what if Gray's feelings for Charlie aren't just sisterly? Not only might this explain her solitary life, but it could lead to real dilemmas - with Charlie (who's sweet, but a bit opaque) and with Sam. No advice comes from Gray's therapist, but a co-worker and a cab driver give theirs. Can Gray sort things out?

A story of love and lies for four twenty-somethings looking to find themselves in New York City. A pair of best friends and a seemingly perfect couple meet at a local Irish pub tucked in the winding streets of the West Village. Through their chance meeting, the four bond and over time all of their relationships with one another morph into love, betrayal and heartbreak for all.

Eager to escape life with her depressive single father, 16-year-old athlete Cyd Loughlin visits her novelist aunt in Chicago over the summer. While there, she falls for a girl in the neighborhood, even as she and her aunt gently challenge each other in the realms of sex and spirit.

Hannah and Rachel grew up as little girls in the same small Midwest town, where traditional gender expectations eventually challenge their deep love for one another. Hannah becomes an adventurous, unapologetic lesbian and Rachel a strong but quiet homemaker. Weaving back and forth between past and present, the film reveals how the women maintained their love affair despite a marriage, a world war, infidelities, and family denial.

The story of five teenage girls who form an unlikely bond after beating up a teacher who has sexually harassed them. They build a solid friendship but their wild ways begin to get out of control.

Claude and Ellen are best friends who live in a not-so-nice area of New York. They're involved in the subculture of '90s youth, complete with drugs, live music, and homophobia. All is changed one night when a violent, meaningless death rocks their lives.

Max is a trendy, pretty, young lesbian, who is having trouble finding love. A friend sets her up with Ely, whom Max likes, but Ely is frumpy, homely, and older. Nor do they have much in common. Can Max learn to look past the packaging?

Lucy and others demonstrate outside a prison about to execute a mentally disabled man for killing a cop. She meets Mercy, who is there with her mom and dad, a cop, to support the execution. Once home again with her big sister Martha and kid brother Ben, Lucy googles Mercy. She's a lawyer. Lucy's dad is to be executed in a few months for allegedly killing her mom 8 years ago, when Lucy was 14 and Ben a baby. Martha has been like a mom for them since. The siblings have a pro bono lawyer trying to get their dad off death row. The cute Mercy keeps meeting up with Lucy.

Annabelle is the wise-beyond-her-years newcomer to an exclusive Catholic girls school. Having been expelled from her first two schools she's bound to stir some trouble. Sparks fly between her and her teacher, Simone Bradley. Annabelle pursues Simone relentlessly until Simone must make a choice between following her heart and doing what's right.

It is 1950s Nevada, and Professor Vivian Bell arrives to get a quickie divorce. She's unsatisfied with her marriage, and feels out of place at the ranch she stays on, she finds herself increasingly drawn to Cay Rivers, an open and self-assured lesbian, and the ranchowner's daughter. The emotions released by their developing intimacy, and Vivian's insecurities about her feelings towards Cay, are played out against a backdrop of rocky landscapes and country and western songs.

Anna is a young lesbian high school graduate who still lives with her parents, and works as a receptionist in a plastic surgeon's office. She embarks on a wild ride when she hooks up with a cadre of ultra-radical feminist lesbians hell-bent on raising hell. But things get even more complicated when Anna falls in love with Sadie, the radical group's leader who's already involved with an older woman named Courtney.

A young woman named Joey has a bright future ahead of her just as long as she can get out of the dead end town that she's in. So just as she's about to make her decision to leave she meets and falls in love with Rayna a married mother of 2 little girls. This is the story about their complicated and somewhat secret love affair.

Jessica Stein is a single, straight, successful, journalist, part of a bonded Jewish family living in New York City, who finds herself not as straight as she thought when Jessica meets and begins an intense friendship with career woman Helen Cooper which ultimately leads to romance.