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Based in Quantico, Virginia, the Behavioral Analysis Unit (B.A.U.) is a subsection of the F.B.I. Called in by local Police departments to assist in solving crimes of a serial and/or extremely violent nature where the perpetrator is unknown (referred to by the Unit as the unknown subject or "unsub" for short), the B.A.U. uses the controversial scientific art of profiling to track and apprehend the unsub. Profiling entails coming up with basic characteristics of the unsub and the victims (referred to as the victimology), using evidence from the case and matching that information to historic precedents and psychological analyses as a means to solve the case. Because of the nature of the work conducted by the B.A.U. - the work being time consuming and psychologically demanding - its members are fiercely loyal to the Unit and to its other members. Also because of the work's overall demanding nature, not many members of the B.A.U. have been able to maintain a happy or stable family life.

A team of detectives investigates stalkers in Los Angeles.

A young CIA operative/trainee, Annie Walker, is sent into the field to work for the DPD (Domestic Protection Division). Auggie Anderson is a blind tech operative, and is Walker's guide in her new life in the CIA. Walker's cover story is that she works at the Smithsonian Museum.

After an embarrassing and public breakdown, Detective Aidan Black (David Sutcliffe) is reassigned from his beloved SWAT team to the newly created Psych Crimes and Crisis Unit. There, he's dismayed to find his partner is not another cop, but forensic psychiatrist, Dr. Daniella Ridley (Stefanie von Pfetten). The unit also includes Detective Poppy Wisnefski (Luisa d'Oliveira) and psychiatric nurse Leo Beckett (Dayo Ade), with Inspector Diane Caligra (Karen LeBlanc) keeping a close watch over the unique partnerships. Passionate and opposing viewpoints are an inherent part of the job in Psych Crimes, and the answers the teams seek never come easy. Aidan's deep insight and investigative skills combine brilliantly with Daniella's keen ability to decipher human behaviour. Learning to work cohesively, the Psych Crimes and Crisis Unit investigates city's most troubling and psychologically complex crimes. Whether or not the unit is still around in a few months... is completely up to them.

In the Los Angeles office of the Federal Bureau of Investigation, Special Agent Don Eppes and his team investigate critical and baffling crimes with a special edge. That advantage is Don's brother, Charles Eppes, a brilliant universalist mathematician who uses the science of mathematics with its complex equations to ferret out the most tricky criminals. With this team, the forces of evil learn their number is up.

A former Chicago cop moves to a small Florida town and joins the state police.

Based on the real life of Walter O'Brien, a genius with an IQ of 197. Walter is asked by Homeland Security to put together a special group of gifted individuals to troubleshoot the most difficult problems that the US & the world may encounter.

Carrie Wells, a former police detective, has a rare ability to remember virtually everything she experiences including detailed visual recall. She returns to police work and uses her ability to solve crimes.

Brilliant, but socially inept, forensic anthropologist Dr. Temperence Brennan works at the Jeffersonian Institute in Washington DC. After consulting for him on a FBI case, she is approached by cocky yet charming Former Army Ranger turned Special Agent, Seeley Booth to help the Bureau solve crimes by identifying human remains that are too far gone for standard FBI forensic investigations. Brennan's empirical, literal view of the world causes friction with Booths emotive, instinctive attitude creating a volatile relationship. However as their case load increases the symbiotic partnership produces results and with the support of Brennan's Squint Squad, murderers, past and present should be on the look out.

The best private pathologist in Miami, Dr. Beaumont Rosewood, Jr., whose rare heart condition that could kill him at any moment fuels his lust for life, gives a second opinion when friends or family of the deceased are not satisfied with official police findings. His state-of-the-art laboratory equipment, Sherlock Holmes-like powers of deduction and quick wit are his main tools. He also relies and depends on his trusty assistants and cute couple, Pippy and TMI, and works with no-nonsense detective Annalise Villa, who doesn't always go strictly by the book, to see the case to its conclusion.

Deputy Police Chief Brenda Leigh Johnson, formerly Atlanta police officer and CIA-trained interrogator, is given the opportunity to run her own division of elite officers of the Los Angeles Police Department. Her unusual procedure for obtaining confessions, blatant disregard for politics, and southern accent make her a marked woman. However, with all the bluster and bravado, she still maintains her title, The Closer.

Detective Jane Rizzoli and Chief Medical Examiner Dr. Maura Isles team up to solve crimes in Boston.

A homicide detective, a medical examiner, a newspaper reporter and a young assistant district attorney work together to solve homicide investigations.

Having lost her medical license in the aftermath of a family tragedy, Megan Hunt M.D. joined the medical examiners and proved herself a forensic genius. Yet even diplomatic Medico-legal Investigator Pete Dunlop can't prevent her arrogant attitude and total disregard for any authority or social norm to cause grave aggravation all around. Still, as long as the perpetrators suffer most, the bulldozer approach pays off on the balance.

The Naval Criminal Investigation Service's Office of Special Projects takes on the undercover work and the hard to crack cases in LA. Key agents are G. Callen and Sam Hanna, streets kids risen through the ranks.

Special Agent Leroy Jethro Gibbs is the leader of a team of special agents belonging to the NCIS (Naval Criminal Investigative Service) Major Case Response Team. Gibbs, a former Marine, is a tough investigator and a highly skilled interrogator who relies on his gut instinct as much as evidence. Gibbs' second in command is Senior Field Agent Tony DiNozzo, a womanizing, movie-quoting former Baltimore Homicide Detective, who despite being the class clown always gets the job done. The team also consists of probationary field agent Eleanor Bishop, a former NSA agent, as well as Junior Field Agent Timothy McGee, a computer-savvy agent often mocked by DiNozzo. Assisting them are Abby Sciuto, the energetic-but-Goth lab tech who is like a daughter to Gibbs, and Dr. Donald Mallard, nicknamed Ducky, the eccentric medical examiner full of unusual stories. This team of elite agents, based in Washington, D.C., solve criminal cases involving Marine and Navy personnel and their families, sometimes traveling the United States - or the world - to do it.

A New York City homicide Detective cracks case after case while raising wild twin boys and locking horns with her less than helpful Police Detective ex-husband.

Dr. Jordan Cavanaugh is a forensic pathologist who lost her job with the Boston medical examiner's office because her passion for solving homicides frequently extended beyond the autopsy table. Years later, an old ally rescues Jordan from court-ordered anger management training in Los Angeles and rehires her to her former job in Boston. Jordan is still feisty and mercurial and a pain in the butt, but management tolerates her because she is good at her job. She and her father, a disgraced former Boston police detective, often solve crimes together by using a role-playing game they've played since Jordan's childhood. It goes: "You be the killer, and I'll be the victim, and we'll figure out how this happened." The driving force in Jordan's life and career is the crime she took the longest time to solve -- her mother's murder.