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As any detective can tell you, investigating missing property or deaths is comparatively easy compared to elusive missing people. However in New York City, there is a special unit of the FBI that is designed to find them. Using the vast resources of their bureau, the team, lead by Agent Jack Malone, race against time in the tight 72 hour window after a disappearance while hope for a recovery is still typically possible.

Living among the citizens of the infamous New Mexico city of Roswell are some who are not there by choice. They are there to follow a destiny given to them by the members of their dying race, a race that they are someday destined to save. This is the background behind the WB series "Roswell". Max Evans, Isabel Evans and Michael Guerin are teenage humans with extraordinary gifts - gifts that are "not-of-this-earth". They are human/alien hybrids, sent here to complete their destiny. Their counterparts have already perished in a war of attrition, thus one day, they will return to their home planet and save their race. Before a fateful day in 1999, the teens hid their gifts. The event that forever changed their lives was when Max healed Liz Parker (a classmate) after she was fatally shot in the stomach in a dispute between two customers at the restaurant where she waitresses. A close relationship then develops between Max and Liz. Central to the first season were the relationships between the hybrids and their human companions. That focus has shifted during the drama's second season. "Roswell" is now distinctly a science-fiction show built on the relationships between humans and aliens.

A well-meaning but struggling writer decides to lead a sort of double life by pretending to be a private detective using the methods he read about in old detective novels.

Mary Shannon is a U.S. Marshal in the witness protection program who spends her time relocating federal witnesses.. Based in Albuquerque, New Mexico, Mary works with her partner, Marshall Mann, to place criminals and innocent witnesses into new lives. When not putting her life on the line to protect federal witnesses, Mary attempts to manage her dysfunctional family, including overly dependent mother, Jinx, and younger sister, Brandi, both of whom live with her. Between work and family, Mary has little time for boyfriend Raphael Ramirez who plays minor league baseball.

In the Los Angeles office of the Federal Bureau of Investigation, Special Agent Don Eppes and his team investigate critical and baffling crimes with a special edge. That advantage is Don's brother, Charles Eppes, a brilliant universalist mathematician who uses the science of mathematics with its complex equations to ferret out the most tricky criminals. With this team, the forces of evil learn their number is up.

Thirty-two year old single mom, Lorelai, lives with her teenage daughter Rory in the small town of Stars Hollow, Connecticut, with crazy neighbors and many ups and downs.

Lilly Rush is a Philadelphia police detective working for the department's homicide squad and being assigned "cold cases": crimes that were committed many years before and have not been solved. Lilly must try to re-think the crime scenes and interview other people involved with the victims to find a link to solving the cases.

Brilliant, but socially inept, forensic anthropologist Dr. Temperence Brennan works at the Jeffersonian Institute in Washington DC. After consulting for him on a FBI case, she is approached by cocky yet charming Former Army Ranger turned Special Agent, Seeley Booth to help the Bureau solve crimes by identifying human remains that are too far gone for standard FBI forensic investigations. Brennan's empirical, literal view of the world causes friction with Booths emotive, instinctive attitude creating a volatile relationship. However as their case load increases the symbiotic partnership produces results and with the support of Brennan's Squint Squad, murderers, past and present should be on the look out.

Richard "Rick" Castle is a millionaire playboy who recently killed off his main character when a serial killer starts killing people like he does in his books. He teams up with New York police detective Kate Beckett to solve the case. He finds inspiration in Detective Beckett and starts shadowing her for his next book.

When she was a deeply troubled teenager, Nikita was rescued from death row by a secret U.S. agency known only as Division, who faked her execution and told her she was being given a second chance to start a new life and serve her country. What they didn't tell her was that she was being trained as a spy and assassin. Throughout her grueling training at Division, Nikita never lost her humanity, even falling in love with a civilian. When her fiancé was murdered, Nikita realized she had been betrayed and her dreams shattered by the only people she thought she could trust, so she did what no one else before her had been able to do: she escaped. Now, after three years in hiding, Nikita is seeking retribution and making it clear to her former bosses that she will stop at nothing to expose and destroy their covert operation.

Deputy Police Chief Brenda Leigh Johnson, formerly Atlanta police officer and CIA-trained interrogator, is given the opportunity to run her own division of elite officers of the Los Angeles Police Department. Her unusual procedure for obtaining confessions, blatant disregard for politics, and southern accent make her a marked woman. However, with all the bluster and bravado, she still maintains her title, The Closer.

He's smart, he's good looking, and he's got a great sense of humor. He's Dexter Morgan, everyone's favorite serial killer. As a Miami forensics expert, he spends his days solving crimes, and nights committing them. But Dexter lives by a strict code of honor that is both his saving grace and lifelong burden. Torn between his deadly compulsion and his desire for true happiness, Dexter is a man in profound conflict with the world and himself. Golden Globe winner Michael C. Hall stars in the hit SHOWTIME Original Series.

Detective Jane Rizzoli and Chief Medical Examiner Dr. Maura Isles team up to solve crimes in Boston.

Having lost her medical license in the aftermath of a family tragedy, Megan Hunt M.D. joined the medical examiners and proved herself a forensic genius. Yet even diplomatic Medico-legal Investigator Pete Dunlop can't prevent her arrogant attitude and total disregard for any authority or social norm to cause grave aggravation all around. Still, as long as the perpetrators suffer most, the bulldozer approach pays off on the balance.

In Seattle, Det. Sarah Linden is on what is supposed to be her last day on the job. She and her son Jack are supposed to leave that evening to join her fiancé in Sonoma. Her replacement, Det. Stephen Holder, is ready to take over but they answer a call from a patrol car who have found a bloodied sweater in a field. When the missing girl, Rosie Larsen, is found in the trunk of a car at the bottom of a lake it turns out the car is registered to the campaign committee for councilman Darren Richmond, who is running for mayor. Linden delays her departure for what she hopes will be only a few days.

Ex-cop and recovering alcoholic Hank Dolworth partners with his best friend, former criminal Britt Pollack, in an unlicensed private investigation business.

Dr. Cal Lightman teaches a course in body language and makes an honest fortune exploiting it. He's employed by various public authorities in various investigations, doing more when the police etc. fail to go the extra mile. So he can afford to constitute a team of his own, which like clients and others has to put up with his mind-games.

Bridget is six months sober and getting her life back on track when she becomes the sole witness to a professional hit. She flees to New York City where she reunites with her estranged twin Siobhan. Wealthy, pampered, and happily married, Siobhan lives a fairy-tale life. Just as the identical twins are mending their frayed relationship, Siobhan disappears overboard during their boat trip, and Bridget decides to take on Siobhan's identity. She discovers shocking secrets, and not just about her sister and her marriage, and realizes she's no safer as Siobhan than as herself.