Christina Ricci stars as Lizzie, a prize-winning student heading off to Harvard where she intends to study journalism and launch a career as a rock music critic. However, Elizabeth's fractured family situation including an errant father (Nicholas Campbell) and a neurotic, bitterly hypercritical mother (Jessica Lange) has led to a struggle with depression. When her all-night, drug-fueled writing binges and emotional instability alienate her roommate and best friend, Ruby (Michelle Williams), as well as both her first (Jonathan Rhys-Meyers) and second (Jason Biggs) boyfriends, Lizzie seeks psychiatric counseling from Dr. Diana Sterling (Anne Heche), who prescribes the wonder drug Prozac. Despite success as a writer that includes a gig writing for Rolling Stone and some mellowing out thanks to her medication, Lizzie begins to feel that the pills are running her life and faces some tough choices about her future.

Driven by the irrepressible, daily need to have a fix, Harley, a homeless, substance-dependent young woman, thinks that she has found true love in the mean streets of bustling New York City. But then, Ilya, her abusive, drug-addled boyfriend, who dominates her vulnerable heart and gives her a reason to live, asks the unthinkable. Suddenly, devotion becomes a cruel word, and only self-sacrifice can bring atonement. Now, desperate Harley is ready to do Ilya's bidding without a second thought; however, before long, she will have to make a tough decision: choose between her love for Ilya and her unbreakable heroin addiction.

The Road Within is about Vincent, a young man suffering from Tourette Syndrome. His mother dies so his estranged father, Robert, is forced to step in. However, Robert's running for political office and doesn't want his son on the campaign trail - so Robert puts Vincent in a clinic that's run by the unconventional Dr. Mia Rose. Once there, Vincent falls in love with an anorexic woman named Marie. Together, they steal Dr. Rose's car, and end up having to kidnap his OCD roommate, Alex, when he threatens to tell on them. With Robert and Dr. Rose in hot pursuit, Vincent, Marie and Alex go on a life changing road trip to deliver the ashes of his mother to the ocean.

Shy, sensitive April is the class virgin, torn between an illicit flirtation with her soccer coach Mr. B and an unrequited crush on sweet stoner Teddy. Emily, meanwhile, offers sexual favors to every boy to cross her path - including both Teddy and his best friend Fred, a life wire without filters or boundaries. As one high school party bleeds into the next - and April and Teddy struggle to admit their mutual affection - Fred's escalating recklessness starts to spiral into chaos.

Seventeen-year-old Anne just fell in love with Sasha, the most popular girl at her LA public high school. But when Anne tells her best friend Clifton - who has always harbored a secret crush - he does his best to get in the way.

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