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Six New Yorkers juggle love, friendship, and the keenly challenging specter of adulthood. Sam Wexler is a struggling writer who's having a particularly bad day. When a young boy gets separated from his family on the subway, Sam makes the questionable decision to bring the child back to his apartment and thus begins a rewarding, yet complicated, friendship. Sam's life revolves around his friends-Annie, whose self-image keeps her from commitment; Charlie and Mary Catherine, a couple whose possible move to Los Angeles tests their relationship; and Mississippi, a cabaret singer who catches Sam's eye.

Spanning several years involving two persons; a young man, a struggling writer and a young woman, an accountant have a one night stand in a hotel room. Despite going their different paths they meet over the next several years in various different hotel rooms across the USA while they travel on business. Despite they are both involved with different people, they find their romantic tryst a getaway from their everyday lives. But as they both mature and grow apart, will they ever learn that they may be soul mates really meant for each other and their secret rendezvous for sex is something more?

Meet the Borgens. William Borgens is an acclaimed author who hasn't written a word since his ex-wife Erica left him 3 years ago for another man. In between spying on Erica and casual romps with his married neighbour Tricia, Bill is dealing with the complexities of raising his teenage children Samantha and Rusty. Samantha is publishing her first novel and is determined to avoid love at all costs - after all she's seen what it has done to her parents. In between hook ups, she meets "nice guy" Lou who will stop at nothing to win her over. Rusty, is an aspiring fantasy writer and Stephen King aficionado, who is on a quest to gain 'life experiences'. He falls for the beautiful, but troubled Kate and gets his first taste of love and a broken heart. A tale of family, love (lost and found), and how endings can make new beginnings. There are no rewrites in life, only second chances.

The summer before college presents two best friends, Lilly and Gerri, with the opportunity to shed their good girl images. Both girls want to lose their virginity and explore another side of who they are. But their dark and different home lives and the introduction of a bad boy, threaten to destroy their friendship without it being the nice coming-of-age summer that the two girls envisioned.

Diana Watts is an English teacher at Westerbrook High School in Austin, Texas. A longtime and continuing undisclosed issue between her and her mother may be only one factor in Diana looking for love in the wrong place. That place is at school, as she has just embarked on a secret affair with one of her students, Eric Tull. This relationship is the most fulfilling she's had in quite some time. A few incidents and the first real close call in being caught leads to Diana calling off the affair several months in, as she finally comes to the understanding that being caught would certainly mean the end of her teaching career and her good reputation. This close time away from Eric also gives Diana the opportunity to look at their relationship through a slightly different perspective, with the old adage of absence making the heart grow fonder kicking in. As such, Diana gets torn between doing what she knows is the right thing by staying away from Eric, or listening to her troubled heart, her growing obsession and need for what she considers love which may make staying away from Eric difficult.

Violet and her two cohorts attempt to help their "less-fortunate" students at Seven Oaks College - primarily by running a Suicide Prevention Centre and offering their off-beat advice whenever they get a chance. Violet's newest rescue is transfer student, Lily, and Violet wants to teach her how to talk and dress properly, and how to select appropriate men to be interested in. Along their way in helping everybody at the college, the damsels teach the fraternity doofi to hit the books, they get their hearts broken, but then attempt to start an international dance craze.

Anna and Jacob fall instantly in love when they meet as students at an L.A. university. But Anna is British and when graduation approaches, Anna decides to stay and violate her student visa rather than returning to England. After a visit home, she is then unable to return to the United States. While fighting customs and immigration battles, Anna and Jacob must decide if their relationship is worth the distance and the hardship.

Sutter Keely lives in the now. It's a good place for him. A high school senior, charming and self-possessed, he's the life of the party, loves his job at a men's clothing store, and has no plans for the future. A budding alcoholic, he's never far from his supersized, whiskey-fortified thirst-master cup. But after being dumped by his girlfriend, Sutter gets drunk and wakes up on a lawn with Aimee Finecky hovering over him. She's different: the "nice girl" who reads science fiction and doesn't have a boyfriend. While Aimee has dreams of a future, Sutter lives in the impressive delusion of a spectacular now, yet somehow, they're drawn together.

Maggie's plan to have a baby on her own is derailed when she falls in love with John, a married man, destroying his volatile marriage to the brilliant and impossible Georgette. But one daughter and three years later, Maggie is out of love and in a quandary: what do you do when you suspect your man and his ex wife are actually perfect for each other?

Celeste and Jesse have been best friends forever. They dated in high school, got married, and now they're getting divorced. Their best friends don't think they can maintain their friendship throughout the dissolution of their marriage, but Celeste and Jesse don't think there will be a problem. But that's before Jesse gets into a relationship that Celeste doesn't think he can handle, and Celeste finds it harder to move on than she originally thought.

Thirty-five-year-old Jesse Fisher, an admissions officer at a New York City post-secondary institution he who loves English and literature, has somewhat lost his passion in life, which includes recently being unceremoniously dumped by his latest girlfriend, who could no longer be the person to prop him up emotionally. He has a chance to find that passion again when he is invited to the retirement dinner of his second-favorite Ohio University college professor, Peter Hoberg, as his time there was when his life held the most passion. Jesse's encounters with five people there may determine if he does find that passion again. They are: Hoberg, who is resisting the notion of retirement; Judith Fairfield, Jesse's favorite professor, although for a different reason than his like of Hoberg; Nat, a free spirit who navigates life at the institution on his own terms; undergraduate student Dean, who Jesse sees as a younger more destructive version of himself; and nineteen-year-old undergraduate student Zibby, who is seemingly wise beyond her years and with who Jesse embarks on a relationship despite their sixteen-year-age difference.

About a recent college grad who returns home while she tries to figure out what to do with her life.

Young writer, Mason Michael Finch, and his girlfriend, Samantha Cooper, live together but they have an open relationship. They have love affairs with different partners whenever they want and then they tell to each other details of their flings.

A teen artist living in 1970s San Francisco enters into an affair with her mother's boyfriend.

For aspiring comedian Donna Stern, everyday life as a female twenty-something provides ample material for her relatable brand of humor. On stage, Donna is unapologetically herself, joking about topics as intimate as her sex life and as crude as her day-old underwear. But when Donna winds up unexpectedly pregnant after a one-night stand, she is forced to face the uncomfortable realities of independent womanhood for the first time. Donna's drunken hookup - and epic lapse in prophylactic judgment - turns out to be the beginning of an unplanned journey of self-discovery and empowerment.

Adam (Mark Ruffalo) has just reached the 5-year mark in his sex addiction sobriety with help from his sponsor Mike (Tim Robbins). New-comer Neil (Josh Gad) seeks out Adam's help hoping that he'll be his mentor, but Neil doesn't have the same maturity and continues to harass women at work, on the street, and on the subway. Adam has also just met Phoebe (Gwyneth Paltrow), who might be perfect for him, but Adam hasn't been in a relationship since he recognized his addiction to sex, and Phoebe doesn't date addicts. As Adam navigates the romantic relationship waters, Mike struggles connecting to his former drug-addicted son who has just returned home, and Neil develops a relationship with another woman in his sex addicts group, but a platonic friendship might be exactly what he needs.

Believing the quote that you are born alone, die alone and everything else is an illusion, George doesn't see the point of life, school, or homework. Then he meets Sally and he now has a reason to go to school and make friends, even if he's not ready to admit to himself or to her that he likes her. The school's principal and art teacher introduce him to an alumni, and successful artist, Dustin, who can help guide George along life's path, but other distractions start surfacing, and George might not even be able to graduate from high school.

Tanner Hall is a vivid peek into the private world of an all-girls boarding school. In a cozy, but run-down New England, the knot of adolescent complexity is unraveled through the coming-of-age stories of four teenage girls.