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Texas greenhorn Joe Buck arrives in New York City for the first time. Preening himself as a real "hustler", he finds that he is the one getting "hustled" until he teams up with down-and-out but resilient outcast Ratso Rizzo. The initial "country cousin meets city cousin" relationship deepens. In their efforts to bilk a hostile world rebuffing them at every turn, this unlikely pair progress from partners in shady business to comrades. Each has found his first real friend.

With the vivid memory of his long-gone childhood friends Max, Patsy, and Cockeye etched in his mind, his ferociously loyal partners-in-crime during their rise to prominence in New York's Prohibition-era Lower East Side, the defeated, penniless, and guilt-ridden former gangster David "Noodles" Aaronson returns to Manhattan. Not knowing what to expect on his mission to shed light on his opaque past, grizzled Noodles reunites with his only living friend Fat Moe after 35 haunted years of self-exile. However, the relentless, piercing sound of culpability stands in the way of finding closure, as the inscrutable content of a well-worn leather suitcase further complicates matters. And now, against the backdrop of a torn conscience, the sad, bittersweet recollections of more than 50 years of love, death, and everything in-between become inextricably intertwined, leading to even more puzzling questions. But what are a man's options when he is left with nothing?

In Detroit, Clarence Worley goes to the movie theater alone on the day of his birthday to watch some movies. The gorgeous Alabama Whitman accidentally drops her popcorn on Clarence and they watch the movie together. Later they go to a diner for pie, and end up having a one night stand. In the morning, Alabama confesses that she is a call-girl hired to spend the night with him, but she has fallen in love with him. In the morning they get married and Clarence goes to the club where she worked to bring her some clothes. However, her pimp Drexl Spivey and his partner beat up Clarence and he reacts by killing them both. Clarence asks for Alabama's suitcase with her clothes and the other girls mistakenly give another one with cocaine. When Clarence discovers the mistake, he decides to travel with Alabama to the house of his friend, the aspiring actor Dick Ritchie, to sell the drug and travel to Mexico. He visits his father Clifford Worley and gives his address to him. But the Sicilian Mafia is the owner of the drug and a group of killers are sent to hunt down Clarnece and Alabama.

A partially handicapped man named Karl is released from a mental hospital, about 20 years after murdering his mother and another person. Karl is often questioned if he will ever kill again, and he shrugs in response saying there is no reason to. Now out of the mental institution, Karl settles in his old, small hometown, occupying himself by fixing motors. After meeting a young boy named Frank, who befriends him, Karl is invited to stay at Frank's house with his mother Linda, who views Karl as a strange but kind and generous man. However, Linda's abusive boyfriend, Doyle, sees things differently in the way rules ought to be run- normally insulting Linda's homosexual friend Vaughan as well as Karl's disabilities, and having wild parties with his friends. As Karl's relationship with Frank grows, he is watchful of Doyle's cruel actions.

The intersecting life stories of Daniel Plainview and Eli Sunday in early twentieth century California is presented. Miner turn oilman Daniel Plainview is a driven man who will do whatever it takes to achieve his goals. He works hard but he also takes advantage of those around him at their expense if need be. His business partner is his son H.W., who in reality he "acquired" when H.W.'s biological single father, who worked on one of Daniel's rigs, got killed in a workplace accident. Daniel is deeply protective of H.W. if only for what H.W. brings to the partnership. Eli Sunday is one in a pair of twins, whose family farm Daniel purchases for the major oil deposit located on it. Eli, the local preacher and a self-proclaimed faith healer, wants the money from the sale of the property to finance his own church. The lives of the two competitive men often clash as Daniel pumps oil off the property and tries to acquire all the surrounding land at bargain prices to be able to build a pipeline to the coast, and as Eli tries to build his own religious empire.

The future is set for Tony and Michael -- owning a neighborhood bar and making deals in the mean streets of New York City's Little Italy. For Charlie, the future is less clearly defined. A small-time hood, he works for his uncle, making collections and reclaiming bad debts. In love with a woman of whom his uncle disapproves (due to her epilepsy) and a friend of her disturbed cousin, Johnny Boy, a near psychotic whose trouble-making threatens them all -- Charlie just cannot reconcile opposing values. A failed attempt to escape (to Brooklyn) moves them all a step closer to a bitter, almost preordained future.

George (Richard Burton) and Martha (Dame Elizabeth Taylor) are a middle-aged married couple, whose charged relationship is defined by vitriolic verbal battles, which underlies what seems like an emotional dependence upon each other. This verbal abuse is fueled by an excessive consumption of alcohol. George being an associate history professor in a New Carthage university where Martha's father is the President adds an extra dimension to their relationship. Late one Saturday evening after a faculty mixer, Martha invites Nick (George Segal) and Honey (Sandy Dennis), an ambitious young biology professor new to the university and his mousy wife, over for a nightcap. As the evening progresses, Nick and Honey, plied with more alcohol, get caught up in George and Martha's games of needing to hurt each other and everyone around them. The ultimate abuse comes in the form of talk of George and Martha's unseen sixteen-year-old son, whose birthday is the following day.

Netting a hefty profit from their latest drug deal, hippies Wyatt and Billy decide to outfit themselves with among other things motorbikes - Wyatt complete in what they call his Captain America gear and similar motif on the bike - and chucking any structure in their lives beyond the want to get there for the event, cycle from their home base of Los Angeles to New Orleans for Mardi Gras in just over a week. They don't plan to spend their proceeds on this trip - they saving that for a more carefree life in Florida after the fact - they sleeping in the great outdoors along the way. While Wyatt is more easy going, believing in the karmic nature and practicality of helping others when they can and in turn asking for help when they need it, Billy is a little more suspicious of the people they encounter, especially in hiding their wad of cash that is stuffed into the gas tank of Wyatt's bike, that money their future. They will find that not all counter-culturalists have the exact same mindset, while they will also find the spiritual and practical connections to others in perhaps the most unlikely of places and people. But they will also ruffle some feathers just for being hippies, arguably in the fear not of them as people but what they represent. Through it all, Wyatt in particular evaluates if the trip ends up being what he expects or wants for his life.

Jim Stark is the new kid in town. He has been in trouble elsewhere; that's why his family has had to move before. Here he hopes to find the love he doesn't get from his middle-class family. Though he finds some of this in his relation with Judy, and a form of it in both Plato's adulation and Ray's real concern for him, Jim must still prove himself to his peers in switchblade knife fights and "chickie" games in which cars race toward a seaside cliff.

In the 1970s, terrorist violence is the stuff of networks' nightly news programming and the corporate structure of the UBS Television Network is changing. Meanwhile, Howard Beale, the aging UBS news anchor, has lost his once strong ratings share and so the network fires him. Beale reacts in an unexpected way. We then see how this affects the fortunes of Beale, his coworkers (Max Schumacher and Diana Christensen), and the network.

In 1937 Los Angeles, private investigator Jake 'J.J.' Gittes specializes in cheating-spouse cases. His current target is Hollis Mulwray, high-profile chief engineer for the Los Angeles Department of Water and Power, whose wife suspects him of infidelity. In following Mulwray, Gittes witnesses some usual business dealings, such as a public meeting for construction of a new dam to create additional water supply for Los Angeles, as fresh water is vital to the growing community during the chronic drought; Mulwray opposes the dam. Eventually Gittes sees Mulwray meeting with an unknown young woman who isn't his wife. Once news of the supposed tryst between Mulwray and this woman hits the media, additional information comes to light that makes Gittes believe that Mulwray is being framed for something and that he himself is being set up. In his investigation of the issue behind Mulwray's framing and his own setup, Gittes is assisted by Mulwray's wife Evelyn, but he thinks she isn't being forthright with him. The further he gets into the investigation, the more secrets he uncovers about the Mulwrays' professional and personal dealings, including Mulwray's former business-partnership with Evelyn's father, Noah Cross. The identity of the unknown woman may be the key to uncovering the whole story.

Blanche DuBois, a high school English teacher with an aristocratic background from Auriol, Mississippi, decides to move to live with her sister and brother-in-law, Stella and Stanley Kowalski, in New Orleans after creditors take over the family property, Belle Reve. Blanche has also decided to take a break from teaching as she states the situation has frayed her nerves. Knowing nothing about Stanley or the Kowalskis' lives, Blanche is shocked to find that they live in a cramped and run down ground floor apartment - which she proceeds to beautify by putting shades over the open light bulbs to soften the lighting - and that Stanley is not the gentleman that she is used to in men. As such, Blanche and Stanley have an antagonistic relationship from the start. Blanche finds that Stanley's hyper-masculinity, which often displays itself in physical outbursts, is common, coarse and vulgar, being common which in turn is what attracted Stella to him. Beyond finding Blanche's delicate hoidy-toidy act as putting on airs, Stanley, a plant worker, believes she may really have sold Belle Reve and is withholding Stella's fair share of the proceeds from them. What further affects the relationship between the three is that Stella is in the early stage of pregnancy with her and Stanley's first child. Soon after her arrival at the Kowalskis, Blanche starts to date Mitch, one of Stanley's friends and coworkers who is a little softer around the edges than most of Stanley's friends. Mitch does not hide the fact that he is looking in general to get married because of a personal issue, he wanting Blanche ultimately to be his wife. Mitch is somewhat unaware that Blanche has somewhat controlled their courtship to put herself in the best possible light, both figuratively and literally. But in Stanley's quest to find out the truth about Belle Reve and Blanche's life in Auriol, the interrelationships between Stanley, Blanche, Stella and Mitch may be irrevocably affected, with any revelation about that life which may further destroy what's left of Blanche's already damaged mental state.

Because his wife left him and took his son with her, screenwriter Ben Sanderson has started drinking, a lot. He's getting more and more isolated and he troubles women in bars because he wants to have sex with them. When he gets fired, he decides to leave everything behind and move to Las Vegas and drink himself to death. In Las Vegas he meets Sera, a prostitute with some problems as well who he moves in with.

Gloria is a young woman of the Depression. She has aged beyond her years and feels her life is hopeless, having been cheated and betrayed many times in her past. While recovering from a suicide attempt, she gets the idea from a movie magazine to head for Hollywood to make it as an actress. Robert is a desperate Hollywood citizen trying to become a director, never doubting he'll make it. Robert and Gloria meet and decide to enter a dance marathon, one of the crazes of the 1930's. The grueling dancing takes its toll on Gloria's already weakened spirit, and she tells Robert that she'd be better off dead, that her life is hopeless - all the while acting cruelly and bitterly, alienating those around her, trying to convince him to shoot her and put her out of her misery. After all, they shoot horses, don't they?

1934. Young adults Bonnie Parker, a waitress, and Clyde Barrow, a criminal just released from prison, are immediately attracted to what the other represents for their life when they meet by chance in West Dallas, Texas. Bonnie is fascinated with Clyde's criminal past, and his matter-of-factness and bravado in talking about it. Clyde sees in Bonnie someone sympathetic to his goals. Although attracted to each other physically, a sexual relationship between the two has obstacles. They decide to join forces to embark on a life of crime, holding up whatever establishments, primarily banks, to make money and to have fun. They don't plan on hurting anyone or killing despite wielding loaded guns. They amass a small gang of willing accomplices, including C.W. Moss, a mechanic to fix whatever cars they steal which is important especially for their getaways, and Buck Barrow, one of Clyde's older brothers. The only reluctant tag-along is Buck's nervous wife, Blanche Barrow, a preacher's daughter. The gang's life changes after the first fatal shot is fired. After that, their willingness to shoot to kill increases to protect themselves and their livelihood. Their notoriety precedes them, so much so that no matter what one's opinion is of them, most want to have some association to the Barrow gang, to help them, to be spoken in the same breath as them, or to capture and or kill them. Of the many people they encounter in their crime spree, the one who may have the most profound effect on their lives is Texas Ranger, Frank Hamer, who seeks retribution.

In tiny Anarene, Texas, in the lull between World War Two and the Korean Conflict, Sonny and Duane are best friends. Enduring that awkward period of life between boyhood and manhood, the two pass their time the best way they know how -- with the movie house, football, and girls. Jacy is Duane's steady, wanted by every boy in school, and she knows it. Her daddy is rich and her mom is good looking and loose. It's the general consensus that whoever wins Jacy's heart will be set for life. But Anarene is dying a quiet death as folks head for the big cities to make their livings and raise their kids. The boys are torn between a future somewhere out there beyond the borders of town or making do with their inheritance of a run-down pool hall and a decrepit movie house -- the legacy of their friend and mentor, Sam the Lion. As high school graduation approaches, they learn some difficult lessons about love, loneliness, and jealousy. Then folks stop attending the second-run features at the movie house and the time comes for the last picture show. With the closure of the movie house, the boys feel that a stage of their lives is closing. They stand uneasily on the threshold of the rest of their lives. (The movie was adapted from the novel by Larry McMurtry).

Frank Galvin was once a promising Boston lawyer with a bright future ahead. An incident early in his career in which he was trying to do the right thing led to him being fired from the prestigious law firm with which he was working, almost being disbarred, and his wife leaving him. Continually drowning his sorrows in booze, he is now an ambulance-chasing lawyer, preying on the weak and vulnerable, and bending the truth whenever necessary to make what few dollars he has, as he has only had a few cases in the last few years, losing the last four. His only friend in the profession is his now retired ex-partner, Mickey Morrissey, who gets Frank a case, his fee solely a percentage of what his clients are awarded. The case should net Frank tens of thousands of dollars by settling out of court, that money which would at least get him back on his feet. It is a negligence suit brought on behalf of Deborah Ann Kaye by her sister and brother-in-law, Sally and Kevin Doneghy, against St. Catherine Labouré Hospital, operated by the Archdiocese of Boston, and Drs. Towler and Marks. Kaye was admitted to the hospital for what should have been a routine delivery, but something that happened while Kaye was on the operating room table led to her brain being deprived of oxygen, resulting in permanent brain damage, and Kaye now being in a totally vegetative state requiring hospitalization for the rest of her life. Frank eventually learns that the cause seems to be that Dr. Towler, the anesthesiologist and an expert in the field, used the incorrect anesthetic for the situation. However, all but one person that was in the operating room that day has provided depositions that nothing improper occurred in the operating room. The one holdout is the operating room head nurse, Maureen Rooney, who is not talking, period, to Frank or the other side. Upon seeing the state Kaye is in, Frank unilaterally decides to do what he believes is the right thing by declining the lucrative out-of-court settlement offered by the Archdiocese and take the case to court. In doing so, he hopes the truth that the hospital and the doctors truly were negligent comes to light. Feeling that this case may be a turning point in his life, Frank has a new spring in his step, enough that he attracts the attention of Laura Fischer, the two who begin a relationship. Despite having whatever the truth is on his side, that truth which he does not know, and having an expert witness of his own, Frank has an uphill battle in that the Archdiocese has retained the services of Ed Concannon, a high-priced lawyer who has a large team of associates whose task is to help Concannon and the Archdiocese win at any cost. Concannon's task seems even easier as Judge Hoyle, the presiding judge, is already biased against Frank for taking the case to court.

McMurphy has a criminal past and has once again gotten himself into trouble and is sentenced by the court. To escape labor duties in prison, McMurphy pleads insanity and is sent to a ward for the mentally unstable. Once here, McMurphy both endures and stands witness to the abuse and degradation of the oppressive Nurse Ratched, who gains superiority and power through the flaws of the other inmates. McMurphy and the other inmates band together to make a rebellious stance against the atrocious Nurse.