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As the world is in the middle of an industrial revolution, a monster appears that cannot be defeated unless its heart, which is protected by a layer of iron, is pierced. By infecting humans with its bite, the monster can create aggressive and undead creatures known as Kabane. On the island Hinomoto, located in the far east, people have built stations to shelter themselves from these creatures. People access the station, as well as transport wares between them, with the help of a locomotive running on steam, called Hayajiro. Ikoma, a boy who lives in the Aragane station and helps to build Hayajiro, creates his own weapon called Tsuranukizutsu in order to defeat the creatures. One day, as he waits for an opportunity to use his weapon, he meets a girl named Mumei, who is excused from the mandatory Kabane inspection. During the night, Ikuma meets Mumei again as he sees Hayajiro going out of control. The staff on the locomotive has turned into the creatures. The station, now under attack by Kabane, is the opportunity Ikoma has been looking for.

Gungrave follows the story of best friends Brandon Heat and Harry MacDowell as they join and rise in the ranks of Big Daddy's Millenion crime syndicate. The story begins in the future revealing Brandon Heat has become a creature now known as Beyond The Grave killing monsters with two very large guns and wicked looking machine gun on his back and that Harry MacDowell is now the Boss of Mellinion and has become a cruel leader who has earned himself the nickname Bloody Harry. The story strafes between the past and the future to reveal why Brandon has become a non-talking monster killer and the series of events that caused Harry to become so evil.

Guts, "The Black Swordsman", is pursued by demons who are attracted to him, due to a demonic brand on his neck. His goal is to free himself, and his lover Casca, of this inescapable curse. His other life's goal is gain vengeance on his former best friend Griffith, who doomed him and his former Band of Mercenaries, to obtain demonic powers of his own. Gut's giant "Dragon Slayer" sword, the Elf Puck and a growing band of misfit companion aid him in his quest for vengeance.

Chronicles the struggles of the cursed Joestar bloodline against the forces of evil. Beginning in 1880, Part I follows Jonathan Joestar as he matures with and eventually combats his adoptive brother, the cunning, merciless Dio Brando. Set in 1938, Part II follows the misadventures of Joseph Joestar, grandson of Jonathan, as he masters the Ripple in order to combat hostile, ancient super-beings named the Pillar Men; creators of the Stone Mask. Part III follows Jotaro Kujo and his group as they journey from Tokyo to Cairo to save his mother's life by defeating his family's resurrected archenemy, Dio. In Part IV, an Arrow manifesting latent Stand abilities travels throughout Morioh, Japan in 1999; as high-schooler Josuke Higashikata (illegitimate son of Joseph) and friends seek out the culprit of a series of decade-long homicides. Set in 2001, Part V follows Giorno Giovanna, son of Dio, and his ambition to rise within the Neapolitan mafia by subverting its most powerful gang: Passione.

In their closed-off underground village, Kamina and Simon chafe at the limits imposed by the village elder. Yet all this will change, when Simon stumbles across a fantastic device - just as the village's peace is broken by a violent intrusion.

In Tokyo, an impenetrable field known as "Hell's Gate" appeared ten years ago. At the same time, psychics who wield paranormal powers at the cost of their conscience also emerged. Hei is one of the most powerful of these psychic agents, and along with his blind associate, Yin, works for one of the many rival agencies vying to unlock the mysteries of Hell's Gate.

Follows the adventures of Koyomi Araragi, a former vampire. One day, a classmate named Hitagi Senjougahara, a loner, falls down the stairs into Koyomi's arms. Hitagi appears to weigh next to nothing, defying physics. Despite being threatened by her to keep away, Koyomi offers his help, and introduces her to Meme Oshino, a strange middle-aged man living in an abandoned building, who cured him of vampirism. Koyomi becomes gradually more involved in cases related to unusual supernatural creatures, meeting new people and discovering secrets in the people he thought he knew.

It is the year 2010. After the great network crash of 2005, online entertainment was restricted. Two years after, the CC Corporation released the first Massively Multiplayer Online Role Playing game since the incident. The extremely popular game, called "The World" sells millions of copies. And when that many are playing, things are bound to go wrong. A mysterious boy, who calls himself Tsukasa, appears. He is very mysterious, and he claims that he is actually alive in real world, but not in front of a terminal. He is branded an illegal player by the Crimson Knights, and is pursued.

In a post-apocalyptic future where humans live in domed cities surrounded by wasteland, wolves are assumed to be two hundred years extinct. Yet wolves do walk among them, disguising themselves as humans in order to survive in the human world. Now four young wolves will follow the scent of Lunar Flowers on a dangerous quest to find that which legend promises them: Paradise.

Twenty-six years ago, in a third-year classroom of a middle school, there was a student named Misaki. As an honors student who was also good at sports, the charming boy was popular with his classmates. When he suddenly died, his classmates decided to carry on as if he was still alive until graduation. Then, in the spring of 1998, a boy named Sakakibara Kouichi transfers to that classroom, and he grows suspicious of the fearful atmosphere in that classroom. In particular, there is a beautiful, aloof girl named Mei Misaki who wears an eye-patch and is always alone drawing pictures.

Honnouji Academy is forcefully ruled by the iron-fisted control of its student council and its president, Satsuki Kiryuuin. Transfer student, Ryuuko Matoi, arrives on campus carrying a giant sword, that is actually half of a scissor. She is looking for the woman who holds the other half of her sword who killed her father. It is said that Satsuki Kiryuuin knows the identity of the killer but when Ryuuko confronts her she is beaten by the student council and their powerful "goku uniforms" whom she cannot match in strength. However, once Ryuuko receives her own "Kamui" by the name of Senketsu , the odds are lifted in her favor.

One night, 14-year-old Madoka Kaname has a terrible nightmare - against the backdrop of a devastated city, she witnesses a girl fight a losing battle against a dreadful being lingering above, while a cat-like magical creature tells Madoka the only way to change that tragic outcome is for her to make a contract with him and become a magical girl. The next day, the teen's dream seemingly becomes reality as the girl she saw in her dream - Homura - arrives at Mitakihara Middle School as a transfer student, mysteriously warning Madoka to stay just the way she is. But when later on she and her best friend Sayaka encounter the same cat-like magical creature from her dream - who introduces himself as Kyubey - the pair discovers that magical girls are real, and what's more, they can choose to become one. All they must do is sign a contract with Kyubey and agree to take on the duty to fight abstract beings called 'witches' that spread despair to the human world, and in return, each one of them will be granted any single wish they desire. However, as Homura's omen suggests, there might be far more to becoming a magical girl than Madoka and Sayaka realize.

Dante the mercenary, runs a detective agency which specializes in "supernatural activity." Most of the jobs he takes are spent battling demons, which leaves him debt. His associates continue to bring him work until one job threatens his very existence.

The Elric brothers' mother is dead and their father has long since abandoned them. Deciding to perform a forbidden human transmutation to bring their mother back, they end up losing their bodies. Now Edward must join the military in order to gain certain alchemical privileges, with his one goal being to restore his brother to his original state. But with war on the horizon it's only a matter of time before they are both forced to question their morals and ultimately decide the value of human life.

There once lived a pirate named Gol D. Roger. He obtained wealth, fame, and power to earn the title of Pirate King. When he was captured and about to be executed, he revealed that his treasure called One Piece was hidden somewhere at the Grand Line. This made all people set out to search and uncover the One Piece treasure, but no one ever found the location of Gol D. Roger's treasure, and the Grand Line was too dangerous a place to overcome. Twenty-two years after Gol D. Roger's death, a boy named Monkey D. Luffy decided to become a pirate and search for Gol D. Roger's treasure to become the next Pirate King.

The 16-year-old Izumi Shinichi lives with his mother and father in a quiet neighborhood in Tokyo. One night, worm-like aliens called Parasytes invade Earth, taking over the brains of human hosts by entering through their ears or noses. One Parasyte attempts to crawl into Shinichi's ear while he sleeps, but fails since he is wearing headphones, and enters his body by burrowing into his arm instead, taking over his right hand and is named Migi. Because Shinichi was able to prevent Migi from traveling further up into his brain, both beings retain their separate intellect and personality. As the duo encounter other Parasytes, they capitalize on their strange situation and gradually form a strong bond, working together to survive. This gives them an edge in battling other Parasytes, who frequently attack the pair upon realization that Shinichi's human brain is still intact. Shinichi feels compelled to fight other Parasytes, who devour humans as food, while enlisting Migi's help.

They are called Chiropterans, ravenous creatures that can change their form, disguising themselves as human beings. Immortal creatures that feed off blood, they hide themselves among us. An organization called the Red Shield has been waging a private war to wipe them out. Now the struggle has grown. Saya Otonashi is a normal high school student who suffers from amnesia; she can't remember anything before the past year of her life. Then one day, a man named Hagi appears and gives her a katana, and her destiny is only partially revealed. The journey for the truth begins...

The Empire of Britannia has invaded Japan using giant robot weapons called Knightmare Frames. Japan is now referred to as Area 11, and its people the 11's. A Britannian who was living in Japan at the time, Lelouch, vowed to his Japanese friend Suzaku that he'd destroy Britannia. Years later, Lelouch is in high school, but regularly skips out of school to go play chess and gamble on himself. One day, he stumbles on terrorists 11's who've stolen a military secret and is caught by a member of the Britannian task force sent after them, who is Suzaku. As the rest of the squad arrives, Suzaku is shot for disobeying orders, while the military secret, a young immortal witch, gives Lelouch the power of Geass, which makes anyone obey any order. While Suzaku is secretly made the pilot of Britannia's brand new prototype Knightmare, Lancelot, Lelouch becomes the masked Zero to lead the rebellion to destroy Britannia once and for all.