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A highly articulate, erudite and intelligent businessman and mastermind, "Red" Reddington, has allegedly been on the "10 Most Wanted List" of various U.S. law enforcement agencies for over 20 years. The legend is that Red is as elusive as he is clever, controlling a labyrinth of creative enterprises, coupled with uncanny ability to gather and finesse information at the drop of a hat. On the first day at FBI for a new female profiler fresh out of Quantico, Red offers to bandy wits with the FBI. Red promises to deliver various criminals and plots previously unknown to any branch of law enforcement... and all Red requests in return is to choose his muse.

As any detective can tell you, investigating missing property or deaths is comparatively easy compared to elusive missing people. However in New York City, there is a special unit of the FBI that is designed to find them. Using the vast resources of their bureau, the team, lead by Agent Jack Malone, race against time in the tight 72 hour window after a disappearance while hope for a recovery is still typically possible.

A superstar magician Cameron Black whose career is ruined by scandal has only one place to turn to practice his art of deception, illusion, and influence, the FBI where he'll become the world's first consulting illusionist, helping the government solve crimes that defy explanation, and trap criminals and spies by using deception.

A Dutch soldier in the 1600's saves the life of a native woman and is granted the power of eternal youth in return. In the 2000's he is a police detective in New York City, and after 400 years, knows just about everything about the way the criminal mind works.

About Jane Timoney, an iconoclastic female detective who has to make her bones in a tough New York precinct that is dominated by men.

Former CIA operative is lured back to his old life when the NYPD needs his help to stop a serial killer. Dr. Dylan Reinhart (Alan Cumming) is a gifted author and university professor living a quiet life teaching psychopathic behavior to packed classes of adoring students. But when top NYPD detective Lizzie Needham (Bojana Novakovic) appeals to him to help her catch a serial murderer who is using Dylan's first book as a tutorial, Dylan is compelled by the case, comes out of retirement and taps into his old skill set. Though Dylan and Lizzie initially clash, when it comes to catching killers, they realize they will make an ideal team if they both trust their instincts. Based on the James Patterson book.

Modern day noir story about Psychiatrist Eldon Chance, who's in a rut. He's middle-aged, his wife wants a divorce, which might put a strain on his relationship with his astute teenage daughter he deeply cares about, and he's getting tired of his professional work. Chance's natural talent for psychoanalysis allows him to easily assess everyone that wants his help but that doesn't mean he can actually cure them or even help them. Everything changes however, when he meets mysterious and attractive Jaclyn Blackstone, who turns out to have both dark secrets and big psychological as well as private problems. But her most immediate problem is her abusive ex-husband Raymond Blackstone, who also happens to be a corrupt cop with connections. Chance falls for Jaclyn and becomes obsessed with helping her but he quickly realizes that he's in over his head. Help eventually comes in the form of a hulking man called D. While clearly a bit unhinged, asocial and disturbed, D is also highly skilled, calculated, smart and efficient and possesses huge knowledge of tactics, weaponry and hand-to-hand combat. He is also highly focused and loyal and agrees to help Chance find a way to deal with the new and dangerous situation he's put himself in over Jaclyn.

In the Los Angeles office of the Federal Bureau of Investigation, Special Agent Don Eppes and his team investigate critical and baffling crimes with a special edge. That advantage is Don's brother, Charles Eppes, a brilliant universalist mathematician who uses the science of mathematics with its complex equations to ferret out the most tricky criminals. With this team, the forces of evil learn their number is up.

Lilly Rush is a Philadelphia police detective working for the department's homicide squad and being assigned "cold cases": crimes that were committed many years before and have not been solved. Lilly must try to re-think the crime scenes and interview other people involved with the victims to find a link to solving the cases.

Malcolm Bright, one of the best criminal psychologists around, uses his twisted genius to help the NYPD solve crimes.

On the streets of San Francisco a team of the Federal Bureau of Investigation's Behavioral Analysis Unit use profiling to catch some of the most horrific serial killers and unidentifiable subjects.

Carrie Wells, a former police detective, has a rare ability to remember virtually everything she experiences including detailed visual recall. She returns to police work and uses her ability to solve crimes.

Richard "Rick" Castle is a millionaire playboy who recently killed off his main character when a serial killer starts killing people like he does in his books. He teams up with New York police detective Kate Beckett to solve the case. He finds inspiration in Detective Beckett and starts shadowing her for his next book.

Dr. Daniel Pierce is an eccentric neuropsychiatrist who uses his unique outlook to help the federal government solve complex criminal cases.

Deputy Police Chief Brenda Leigh Johnson, formerly Atlanta police officer and CIA-trained interrogator, is given the opportunity to run her own division of elite officers of the Los Angeles Police Department. Her unusual procedure for obtaining confessions, blatant disregard for politics, and southern accent make her a marked woman. However, with all the bluster and bravado, she still maintains her title, The Closer.

A government scientist and his tough attractive FBI handler try to save people from deadly scientific experiments, poisoners, rare diseases, and environmental hazards.

Catherine Black, a famed neuroscientist with a job at the Center for Neurological Research and Treatment, struggles with mental illness. However, this is just one of the many secrets she hides from her fiancé and her family.

Dr. Cal Lightman teaches a course in body language and makes an honest fortune exploiting it. He's employed by various public authorities in various investigations, doing more when the police etc. fail to go the extra mile. So he can afford to constitute a team of his own, which like clients and others has to put up with his mind-games.