WATCH

ROYAL PAINS centers on a young E.R. doctor who, after being wrongly blamed for a patient's death, moves to the Hamptons and becomes the reluctant "doctor for hire" to the rich and famous. When the attractive administrator of the local hospital asks him to treat the town's less fortunate, he finds himself walking the line between doing well for himself and doing good for others.

As any detective can tell you, investigating missing property or deaths is comparatively easy compared to elusive missing people. However in New York City, there is a special unit of the FBI that is designed to find them. Using the vast resources of their bureau, the team, lead by Agent Jack Malone, race against time in the tight 72 hour window after a disappearance while hope for a recovery is still typically possible.

A young CIA operative/trainee, Annie Walker, is sent into the field to work for the DPD (Domestic Protection Division). Auggie Anderson is a blind tech operative, and is Walker's guide in her new life in the CIA. Walker's cover story is that she works at the Smithsonian Museum.

Former insurance claims investigator Nathan Ford heads a team of former top-criminals. They handle 'unorthodox' cases of people unlikely to get their due through regular channels and legal procedures. That often involves stinging or otherwise scamming criminals. Nate's team is altered at times, and his professional as well as personal past repeatedly seems to catch up.

Mary Shannon is a U.S. Marshal in the witness protection program who spends her time relocating federal witnesses.. Based in Albuquerque, New Mexico, Mary works with her partner, Marshall Mann, to place criminals and innocent witnesses into new lives. When not putting her life on the line to protect federal witnesses, Mary attempts to manage her dysfunctional family, including overly dependent mother, Jinx, and younger sister, Brandi, both of whom live with her. Between work and family, Mary has little time for boyfriend Raphael Ramirez who plays minor league baseball.

Walter Sherman is an Iraq war veteran who has suffered brain damage in an IED explosion. The brain damage triggers in Walter the ability to "find" things, he sees connections between seemingly unrelated events, objects or people that other investigators would miss. Walter is assisted by his "legal advisor" and bar owner Leo Knox, US Deputy Marshal Isabel Zambada, and teen parolee and thief Willa Monday, who is serving her probation with the team. The brain damage that gives Walter his "finder" talent has also left him with a case of paranoia and other mental idiosyncrasies. Walter refuses treatment because he does not want to lose his talent. The last time Walter failed to find someone, it was the IED explosive expert that was responsible for blowing up Walter's Humvee and killing 6 members of his unit.

A former Chicago cop moves to a small Florida town and joins the state police.

Lilly Rush is a Philadelphia police detective working for the department's homicide squad and being assigned "cold cases": crimes that were committed many years before and have not been solved. Lilly must try to re-think the crime scenes and interview other people involved with the victims to find a link to solving the cases.

On the streets of San Francisco a team of the Federal Bureau of Investigation's Behavioral Analysis Unit use profiling to catch some of the most horrific serial killers and unidentifiable subjects.

Richard "Rick" Castle is a millionaire playboy who recently killed off his main character when a serial killer starts killing people like he does in his books. He teams up with New York police detective Kate Beckett to solve the case. He finds inspiration in Detective Beckett and starts shadowing her for his next book.

Dr. Daniel Pierce is an eccentric neuropsychiatrist who uses his unique outlook to help the federal government solve complex criminal cases.

Deputy Police Chief Brenda Leigh Johnson, formerly Atlanta police officer and CIA-trained interrogator, is given the opportunity to run her own division of elite officers of the Los Angeles Police Department. Her unusual procedure for obtaining confessions, blatant disregard for politics, and southern accent make her a marked woman. However, with all the bluster and bravado, she still maintains her title, The Closer.

Detective Jane Rizzoli and Chief Medical Examiner Dr. Maura Isles team up to solve crimes in Boston.

The Naval Criminal Investigation Service's Office of Special Projects takes on the undercover work and the hard to crack cases in LA. Key agents are G. Callen and Sam Hanna, streets kids risen through the ranks.

Special Agent Leroy Jethro Gibbs is the leader of a team of special agents belonging to the NCIS (Naval Criminal Investigative Service) Major Case Response Team. Gibbs, a former Marine, is a tough investigator and a highly skilled interrogator who relies on his gut instinct as much as evidence. Gibbs' second in command is Senior Field Agent Tony DiNozzo, a womanizing, movie-quoting former Baltimore Homicide Detective, who despite being the class clown always gets the job done. The team also consists of probationary field agent Eleanor Bishop, a former NSA agent, as well as Junior Field Agent Timothy McGee, a computer-savvy agent often mocked by DiNozzo. Assisting them are Abby Sciuto, the energetic-but-Goth lab tech who is like a daughter to Gibbs, and Dr. Donald Mallard, nicknamed Ducky, the eccentric medical examiner full of unusual stories. This team of elite agents, based in Washington, D.C., solve criminal cases involving Marine and Navy personnel and their families, sometimes traveling the United States - or the world - to do it.

Dr. Cal Lightman teaches a course in body language and makes an honest fortune exploiting it. He's employed by various public authorities in various investigations, doing more when the police etc. fail to go the extra mile. So he can afford to constitute a team of his own, which like clients and others has to put up with his mind-games.

A New York City homicide Detective cracks case after case while raising wild twin boys and locking horns with her less than helpful Police Detective ex-husband.

Dr. Jordan Cavanaugh is a forensic pathologist who lost her job with the Boston medical examiner's office because her passion for solving homicides frequently extended beyond the autopsy table. Years later, an old ally rescues Jordan from court-ordered anger management training in Los Angeles and rehires her to her former job in Boston. Jordan is still feisty and mercurial and a pain in the butt, but management tolerates her because she is good at her job. She and her father, a disgraced former Boston police detective, often solve crimes together by using a role-playing game they've played since Jordan's childhood. It goes: "You be the killer, and I'll be the victim, and we'll figure out how this happened." The driving force in Jordan's life and career is the crime she took the longest time to solve -- her mother's murder.