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Despondent over his breakup with Desiree, Zia slashes his wrists and goes to an afterlife peopled by suicides, a high-desert landscape dotted by old tires, burned-out cars, and abandoned sofas. He gets a job in a pizza joint. By chance, Zia learns that Desiree offed herself a few months after he did, and she's looking for him. He sets off with Eugene (an electrocuted Russian rocker) to find her, and they pick up a hitchhiker, Mikal, who's looking for the People in Charge, believing she's there by mistake. They're soon at the camp of Kneller, where casual miracles proliferate. They hear rumors of a miraculous king. Can Zia find Desiree? Then what? Where there's death there's hope.

In small-town Washington state in 1964, Czechoslovakian immigrant Selma Jezková and her preteen son Gene live in a rented trailer owned by Bill and Linda Houston; Bill is the town sheriff. Selma also has a small group of friends, including her co-worker and primary confidante Kathy, and Jeff, who wants to be her boyfriend. Jeff regularly waits outside Selma's workplace to drive her home, although she always refuses, not wishing to lead him on. Her primary job is working on the Anderson Tool factory assembly line, but she does whatever else she can to earn money. What only Kathy knows among Selma's friends is that she is slowly going blind from a genetic medical condition. She can see just enough to be able to do her job. Her primary reason for moving to the USA and working all the time is to earn enough money for an operation for Gene when he turns 13; he knows nothing about his mother's or his own degenerative eyesight. Selma allows only one indulgence in her life: anything to do with musicals which she loves, because they're an escape from her bleak life. Kathy often takes her to the cinema to watch old musicals and must describe to her what's happening on the screen, to the other patrons' annoyance. Selma also has the role of Maria in a community-theatre production of "The Sound of Music." Close to having enough money for the operation, Selma races against time before she loses enough sight to lose her job and her role in the musical. What may also threaten Selma's goal of the operation for Gene is some financial problems facing Bill, who feels pressured to provide Linda with the comforts of life to which she's accustomed.

Eva's a mother trying to piece together her life following an incident caused by her odd child, Kevin. Once a successful writer, she's forced to take whatever comes her way, in spite of the increasingly bizarre and dangerous things Kevin says, or does.

Sara Goldfarb (Ellen Burstyn) is a retired widow, living in a small apartment. She spends most of her time watching TV, especially a particular self-help show. She has delusions of rising above her current dull existence by being a guest on that show. Her son, Harry (Jared Leto) is a junkie but along with his friend Tyrone (Marlon Wayans) has visions of making it big by becoming a drug dealer. Harry's girlfriend Marion (Jennifer Connelly) could be fashion designer or artist but is swept along in Harry's drug-centric world. Meanwhile Sara has developed an addiction of her own. She desperately wants to lose weight and so goes on a crash course involving popping pills, pills which turn out to be very addictive and harmful to her mental state.

In this comedy, Lars Lindstrom is an awkwardly shy young man in a small northern town who finally brings home the girl of his dreams to his brother and sister-in-law's home. The only problem is that she's not real - she's a sex doll Lars ordered off the Internet. But sex is not what Lars has in mind, but rather a deep, meaningful relationship. His sister-in-law is worried for him, his brother thinks he's nuts, but eventually the entire town goes along with his delusion in support of this sweet natured boy that they've always loved.

Enid and Rebecca after they finish the high school. Both have problems relating to people and they spend their time hanging around and bothering creeps. When they meet Seymour who is a social outsider who loves to collect old 78 records, Enid's life will change forever.

Puppeteer Craig Schwartz and animal lover and pet store clerk Lotte Schwartz are just going through the motions of their marriage. Despite not being able to earn a living solely through puppeteering, Craig loves his profession as it allows him to inhabit the skin of others. He begins to take the ability to inhabit the skin of others to the next level when he is forced to take a job as a file clerk for the off-kilter LesterCorp, located on the five-foot tall 7½ floor of a Manhattan office building. Behind one of the filing cabinets in his work area, Craig finds a hidden door which he learns is a portal into the mind of

Precocious Oliver struggles with being popular in school but when a dark-haired beauty takes interest in him, he's determined to become the best boyfriend in the world. Meanwhile, his parents' already rocky relationship is threatened when his mother's ex-boyfriend moves in next door. Oliver makes some unorthodox plans to ensure that his parents stay together and that Jordana still likes him.

Middle-aged American movie star Bob Harris is in Tokyo to film a personal endorsement Suntory whiskey ad solely for the Japanese market. He is past his movie star prime, but his name and image still have enough cachet for him to have gotten this lucrative $2 million job. He has an unsatisfying home life where his wife Lydia follows him wherever he goes - in the form of messages and faxes - for him to deal with the minutiae of their everyday lives, while she stays at home to look after their kids. Staying at the same upscale hotel is fellow American, twenty-something recent Yale Philosophy graduate Charlotte, her husband John, an entertainment still photographer, who is on assignment in Japan. As such, she is largely left to her own devices in the city, especially when his job takes him out of Tokyo. Both Bob and Charlotte are feeling lost by their current situations, which are not helped by the cultural barriers they feel in Tokyo, those cultural barriers extending far beyond just not knowing the language. After a few chance encounters in the hotel, they end up spending much of their time hanging out together, each helping the other deal with their feelings of loss in their current lives. The friendship that develops between the two, which is not always a bumpy-free one, may be just for this specific place and time, but it may also have long lasting implications.

Billy is released after five years in prison. In the next moment, he kidnaps teenage student Layla and visits his parents with her, pretending she is his girlfriend and they will soon marry (and forcing her to say the same).

A gay teenage prostitute and another teen, both from the same small town in Kansas, narrate separate stories from their childhoods. The prostitute's story is about a disturbing homosexual encounter with his pedophile baseball coach, and the other teen's story revolves around an amnesia blackout during which he thinks he may have been abducted by aliens. Later, the second teen finds clues linking the gay prostitute (now living in New York City) to his possible alien abduction, so he tracks him down to finally seek out the truth.

Eleven separate vignettes are presented. In each, celebrities, playing semi-fictionalized versions of themselves (with the exception of the characters of various wait staff, and one actor playing a lookalike cousin of herself), meet in a food service establishment with coffee/tea and cigarettes involved. Beyond the topic of discussion that brought them together, they often talk directly about coffee and cigarettes, more often that coffee and cigarettes, and by association caffeine and nicotine, are not healthy, especially if they are the only things constituting lunch. Other recurring themes include the Lee family, cousinhood, celebrity worship, the connection between the medical and musical careers, and Nikola Tesla's belief that the Earth is a conductor of acoustic resonance. In all cases, the coming together for coffee/tea and smokes acts as a bridge to overcome disagreements, and/or makes uncomfortable situations less uncomfortable.

A woman breaks up with her boyfriend, he thinks it's because he's fat. A man is unable to tell her next door neighbor he finds her sexually attractive. An old couple wants to split up, but they don't want to get a divorce. A therapist masturbates to teen magazines. An 11 year old kid is insecure about the fact that he hasn't cum yet. Office workers try to recall the face of a coworker who recently died. A woman is sure she has everything she could ever want. The lives of these individuals intertwine as they go about their lives in their own unique ways, engaging in acts society as a whole might find disturbing in a desperate search for human connection.

What's Eating Gibert Grape is a beautifully shot movie of tenderness, caring and self-awareness that is set amongst the fictional working class one street town Endora. Centred around the Grape family Ellen and Amy and their two brothers Arnie and Gilbert, who, along with their morbidly obese widowed mother Bonnie Grape are striving to survive and coexist with the absence of a father figure, low wage work and seventeen-year-old Arnie's severe mental condition. It is in this awkward and extremely one sided affair that the unfortunate Gilbert has to constantly, while working for the town's slowly dying convenience store, take care of his younger brother Arnie. Gilbert's life, his future, is thwarted he knows this, but it is in this guardian angel that his love and bond for Arnie cannot, and will not, be let go. That is until the free spirit of Becky arrives in town, and with her grandmother are stranded for the week while waiting for parts for their vehicle. This realization unties new feelings, new thoughts and new hope for the put upon Gibert, something new is eating Gilbert Grape.

Three grown prodigies, all with a unique genius of some kind, and their mother are staying at the family household. Their father, Royal had left them long ago, and comes back to make things right with his family.

The big-screen version of Hunter S. Thompson's seminal psychedelic classic about his road trip across Western America as he and his large Samoan lawyer searched desperately for the "American dream"... they were helped in large part by the huge amount of drugs and alcohol kept in their convertible, The Red Shark.

In Albuquerque, Sheryl Hoover brings her suicidal brother Frank to the breast of her dysfunctional and emotionally bankrupted family. Frank is homosexual, an expert in Proust. He tried to commit suicide when he was rejected by his boyfriend and his great competitor became renowned and recognized as number one in the field of Proust. Sheryl's husband Richard is unsuccessfully trying to sell his self-help and self-improvement technique using nine steps to reach success, but he is actually a complete loser. Her son Dwayne has taken a vow of silence as a follower of Nietzsche and aims to be a jet pilot. Dwayne's grandfather Edwin was sent away from the institution for elders (Sunset Manor) and is addicted in heroin. When her seven-year-old daughter Olive has a chance to dispute the Little Miss Sunshine pageant in Redondo Beach, California, the whole family travels together in their old Volkswagen Type 2 (Kombi) in a funny journey of hope of winning the talent contest and to make a dream come true.

A day in the lives of a group of average teenage high school students. The film follows every character and shows their daily routines. However two of the students plan to do something that the student body won't forget.