In Rome, the America tourist Hayley meets the local lawyer Michelangelo on the street and soon they fall in love with each other. Hayley's parents, the psychiatrist Phyllis and the retired music producer Jerry, travel to Rome to meet Michelangelo and his parents. When Jerry listens to Michelangelo's father Giancarlo singing opera in the shower, he is convinced that he is a talented opera singer. But there is a problem: Giancarlo can only sing in the shower. The couple Antonio and Milly travel to Rome to meet Antonio's relatives that belong to the high society. Milly goes to the hairdresser while Antonio waits for her in the room. Milly gets lost in Rome and the prostitute Anna mistakenly goes to Antonio's room. Out of the blue, his relatives arrive in the room and they believe Anna is Antonio's wife. Meanwhile the shy Milly meets her favorite actor Luca Salta (Antonio Albanese) and goes to his hotel room "to discuss about movies". One day, the middle-class clerk Leopoldo becomes a celebrity and is hunted by the paparazzo. A couple of days later, he is forgotten by the media. The American architect John travels to Rome with his wife and feels nostalgic since he lived in the city thirty years ago when he was a student. He meets the student of architecture Jack, who lives on the same street that John had lived, and he invited to drink a coffee at his house. Jack lives with his girlfriend Sally (Greta Gerwig) that invites her best friend Monica to stay with them in their house. But soon Jack has a crush on Monica.

Jerry Falk (Jason Biggs) and David Dobel (Woody Allen), who meet at a business meeting, become fast friends. Their commonality is that they are both fledgling New York City based comedy writers, largely writing material for stand-ups, are Jewish (although David is an atheist), and are each of bundle of different neuroses. Their big difference is that Jerry is twenty-one, while David is sixty, with forty more years worth of life experience, knowledge, and neuroses. While Jerry writes full time - he is also working on a novel - David has kept his day job as a public school teacher just in case. In their relationship, David becomes somewhat of Jerry's mentor, providing advice on Jerry's life issues, most which revolve around the fact that Jerry is a product of inertia, having trouble leaving anyone. That's why Jerry's still with the only manager he's ever had, Harvey Wexler (Danny DeVito). Jerry not only being Harvey's only client (which is a testament to his effectiveness in the job), Harvey also has a twenty-five percent take as stipulated in their contract, which he wants to extend for another seven years. That's why Jerry is still in therapy with a psychiatrist who has done him no good, and who advised Jerry to stay in therapy with him as opposed to taking a job in Los Angeles, California. But that not being able to leave largely applies to his love life. Jerry already has one divorce. He is having problems with his current girlfriend Amanda (Christina Ricci), who he believes is the love of his life. He fell in love with her at first sight, when he was already in a cohabitational relationship with Brooke (KaDee Strickland), and Amanda dating Jerry's friend, Bob Stiles (Jimmy Fallon). Even after Jerry began sleeping with Amanda, he could not be up front with Brooke about the situation, leaving her to figure out his lies. What Jerry is unable or unwilling to see is that Amanda not only manipulates him, but that he focuses on the things between them that make them truly compatible, while disregarding those many more things which make them incompatible. What has made their relationship more difficult of late is that her mother, who is trying to find herself, has moved in with them in their small apartment. Despite David's unique view of life, he may be able to see Jerry and Amanda's relationship more clearly as an objective bystander. The question becomes how much of David's advice Jerry will take in its entirety.

Paris, je t'aime is about the plurality of cinema in one mythic location: Paris, the City of Love. Twenty filmmakers have five minutes each; the audience must weave a single narrative out of twenty moments. The 20 moments are fused by transitional interstitial sequences and also via the introduction and epilogue. Each transition begins with the last shot of the previous film and ends with the first shot of the following film, extending the enchantment and the emotion of the previous segment, preparing the audience for a surprise, and providing a cohesive atmosphere. There's a reappearing mysterious character who is a witness to the Parisian life. A common theme of Paris and love fuses all.

Gil and Inez travel to Paris as a tag-along vacation on her parents' business trip. Gil is a successful Hollywood writer but is struggling on his first novel. He falls in love with the city and thinks he and Inez should move there after they get married, but Inez does not share his romantic notions of the city or the idea that the 1920s were the golden age. When Inez goes off dancing with her friends, Gil takes a walk at midnight and discovers what could be the ultimate source of inspiration for writing. Gil's daily walks at midnight in Paris could take him closer to the heart of the city but further from the woman he's about to marry.

Follows a pair of married couples, Alfie (Sir Anthony Hopkins) and Helena (Gemma Jones), and their daughter Sally (Naomi Watts) and husband Roy (Josh Brolin), as their passions, ambitions, and anxieties lead them into trouble and out of their minds. After Alfie leaves Helena to pursue his lost youth and a free-spirited call girl named Charmaine (Lucy Punch), Helena abandons rationality and surrenders her life to the loopy advice of a charlatan fortune teller. Unhappy in her marriage, Sally develops a crush on her handsome art gallery owner boss, Greg (Antonio Banderas), while Roy, an author nervously awaiting the response to his latest manuscript, becomes moonstruck over Dia (Freida Pinto), a mystery woman who catches his gaze through a nearby window.

Al, Louise, Max and Sy - four literary types who work in the theater business - are discussing what they believe to be the real life truths underlying their work, Max who writes primarily tragic plays, and Sy who writes primarily comic plays. Al proceeds to tell them a real story of a troubled woman named Melinda Robicheaux showing up unexpectedly at a door in the middle of an important business dinner party. Melinda long ago left her physician husband to embark on a relationship with who she initially believed to be the man of her dreams, which ended up not being the case. Melinda tries to put her life back together with the help of select people at the dinner party, some who have their own ulterior motives. Melinda's appearance also opens up the cracks existing in the marriage of one of the couples at the dinner party, while it leads to the dissolution of a friendship that has existed since college. With this basic outline of a story, Max and Sy try to make their point of life being truly a tragedy or comedy on spinning Melinda's story with their own mindset.

Jasmine French used to be on the top of the heap as a New York socialite, but now is returning to her estranged sister in San Francisco utterly ruined. As Jasmine struggles with her haunting memories of a privileged past bearing dark realities she ignored, she tries to recover in her present. Unfortunately, it all proves a losing battle as Jasmine's narcissistic hangups and their consequences begin to overwhelm her. In doing so, her old pretensions and new deceits begin to foul up everyone's lives, especially her own.

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