In 1902, in London, spinster Beatrix Potter (Renée Zellweger) lives with her bourgeois parents. Her snobbish mother, Helen Potter (Barbara Flynn), had introduced several bachelors to Beatrix until she was twenty-years-old, but she had turned them all down. Beatrix Potter has been drawing animals and making up stories about them since she was a child, but her parents have never recognized her as an artist. One day, Miss Potter offers her stories to a print house, and a rookie publisher, Norman Warne (Ewan McGregor), who is delighted with her tales, publishes her first children's book. This success leads Norman to publish two other books, and Miss Potter meanwhile becomes the best friend of his single sister Millie Warne (Emily Watson). Soon Beatrix and Norman fall in love with each other, but Helen does not accept that her daughter would marry a "trader". However, Beatrix's father Rupert Potter (Bill Paterson) proposes that his daughter spend the summer with his wife and him in their country house in Lake District, and if she is still interested in Norman after the summertime, he would bless their marriage. When Miss Potter stops receiving letters from Norman, she is disappointed. Then one day she receives a letter from Millie explaining what had happened to Norman.

The Countess Sofya Andreevna Tolstoy (Dame Helen Mirren), wife and muse to Leo Tolstoy (Christopher Plummer), uses every trick of seduction on her husband's loyal disciple, whom she believes was the person responsible for Tolstoy signing a new will that leaves his work and property to the Russian people.

In 1904, in Dublin, James Joyce chats up Nora Barnacle, a hotel maid recently come from Galway. She enchants him with her frank, direct and uninhibited manner, and before long, he's convinced her to come with him to Trieste, where he has a job with Berlitz. Over time, Nora pulls him through phobias, tolerates his drinking, takes in his brother Stan, and bests Joyce at 'the writin' game' to bring him back to Italy from Dublin where he's gone to open a cinema. But his sexual jealousy threatens the relationship and sends her back to Galway with the children. Is there any way to tame Jim's green-eyed monster? And, will the lad ever get his stories published?

1930's rural Nova Scotia. Maud Dowley, who suffers from rheumatoid arthritis, smokes heavily to deal with the pain. Because of her unusual gait from the arthritis, she is often mistaken as a stupid, incapable woman, that perception which does make her feel stupid and incapable. That view is held by her surviving family, her brother Charlie and her Aunt Ida with whom she lives. After an action by Charlie, Maud decides to seek some independence and is the only applicant for a posted job as housekeeper for brusque Everett Lewis, a poor fish seller. Despite not wanting to hire a cripple which only adds to their antagonism, Maud negotiates to get the job for room and board. Their antagonistic relationship ends up including Everett exacting beatings on Maud whenever she doesn't do what he wants. To keep herself happy, Maud begins to paint the interior of the house with happy pictures and paint similar pictures on small cards, these folk art pictures are how she wants to see the world. Maud's paintings come to the attention of one of Everett's customers, Sandra, a New York socialite, who ultimately commissions Maud to paint some pictures for her if Maud won't or can't sell what she's already painted. This begins Maud's possible independence from her violent relationship with Everett, who in turn admits that he may need Maud more than she needs him. In the process, Maud is able to revisit an issue from her past which she believed had long died in a literal sense.

Set in the 1790s, Love and Friendship centers on beautiful widow Lady Susan Vernon, who has come to the estate of her in-laws to wait out colorful rumors about her dalliances circulating through polite society. Whilst there, she decides to secure a husband for herself and her rather reluctant debutante daughter, Frederica.

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