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The FBI examines various crimes all somehow relating to the kidnapping of Sara, U.S. senator Jeffrey Collins's second wife, from Atlanta. First FBI special agent Graham Kelton is in charge, who proved his value in a previous kidnapping case but was traumatized for life by its ending, costing the life of his own son Nathan, takes charge, but quickly finds he's not just dealing with ransom-thieves but facing a complex conspiratorial web involving the senator's crucial political role, notably in judge Wallace Rainer's presidential nomination to the Supreme Court, his first wife Jessica Nevins, their teenage children Max and Marcy, and probably even Nathan's kidnapper-murderer. After Graham's murder in the line of duty, well-connected Special Agent Danny Lucas, dropped from the top, proves as competent and tenacious but faces new, mysterious complications.

Will Travers is an analyst at a New York City-based federal intelligence agency who is thrown into a story where nothing is as it appears to be.

A Dutch soldier in the 1600's saves the life of a native woman and is granted the power of eternal youth in return. In the 2000's he is a police detective in New York City, and after 400 years, knows just about everything about the way the criminal mind works.

Sydney Bristow (Jennifer Garner) is a young, athletic, college graduate who was recruited her freshman year as a Secret Agent for SD-6, a top-secret branch of the C.I.A. After a few years, after Sydney confides her lifestyle to her boyfriend, the evil head of SD-6, Arvin Sloane (Ron Rifkin), has him killed. Sydney learns that SD-6 is part of a rogue international agency called the Alliance of 12, out to rule the world. She becomes a double agent, working with the real C.I.A. to bring down SD-6 with the assistance of her handler, Michael Vaughn (Michael Vartan), and her estranged father Jack Bristow (Victor Garber), also a double agent. Along the way, Sydney fights various rival agents, rival terrorist groups, and traitors all the while keeping her cloak-and-dagger lifestyle a secret from her friends (season one).

This grounded new thriller follows Mara Kint, a former hostage negotiator and expert on human behavior, who became a college professor after facing an unimaginable personal tragedy. But when she's brought in to save ordinary people who have lost themselves in a highly advanced virtual-reality program in which you can literally live your dreams, she finds that in saving others, she may actually have discovered a way to save herself.

Two agents from two different continents, and two different mindsets, must work together to investigate when wreckage from a destroyed alien spacecraft has mysterious effects on humankind.

A man attempts to thwart a giant corporation that seems to have unlimited power.

Lt. Hobbes, a young idealistic Marine who's about to get married, is sent on a top secret mission into "Harsh Realm", a virtual reality world created by the military to run war game scenarios that's identical to his own, to assassinate the renegade soldier Omar Santiago, who has taken control over the game from within and created his own military dictatorship there. In the game, Hobbes meets people like Mike Pinocchio, a tough cynical rogue soldier previously sent on the same mission, Mike's no-nonsense mute female comrade, as well as virtual simulations of the people from the real world including the one based on his real life fiancee. However, he also learns that he is actually trapped in the game along with numerous other soldiers previously sent to kill Santiago. Meanwhile, Hobbes real life fiancee investigates his disappearance with the help of a mysterious female ally with an agenda of her own.

Three families are torn apart when a stranded female soldier, a disillusioned corporate attorney and a disrespected political activist are pulled into the same shocking international military conspiracy.

Taken spans five decades and four generations, centering on three families: the Keys, Crawfords, and Clarkes. World War II veteran Russell Keys is plagued by nightmares of his abduction by aliens during the war; the Roswell incident transforms Owen Crawford from ambitious Air Force captain to evil shadow government conspirator; the unhappily married Sally Clarke is impregnated by an alien visitor. As the decades go by, the heirs of each are affected by the machinations of the aliens, culminating with the birth of Allie Keys, who is the final product of the aliens' experimentation and holds the key to their future.

The 4400 explores the travails of the 4400 people who all at once returned in a ball of light to Earth; though the returnees had not aged physically, many of them reappeared with dramatic abilities ranging from enhanced reflexes to precognition. NTAC (National Threat Assessment Command) is the government agency responsible for keeping track of the returnees and investigating all things related to the 4400.

A government scientist and his tough attractive FBI handler try to save people from deadly scientific experiments, poisoners, rare diseases, and environmental hazards.

16-year-old Henry Coles is an outsider in her new town of Reston, New York. With a major chip on her shoulder and no friends, she remains withdrawn and isolated, but everything changes when a traumatic encounter with a classmate triggers something deep within Henry- unleashing a power she cannot control.

A billionaire software-genius named Harold Finch creates a Machine for the government that is designed to detect acts of terror before they can happen, by monitoring the entire world through every cell-phone, email and surveillance camera. Finch discovered that the machine sees everything, potential terrorist acts and violent crimes that involve ordinary people. When the government considered violent crimes between normal people "irrelevant", Finch built a back door into the system that gives him the social security number of a person involved in a future violent crime so he could act. Partnered with John Reese, an ex-CIA agent, the two work in secret to prevent violent crimes before they can happen. Eventually their activities lead to being hunted by the New York Police Department, CIA Agents in pursuit of Reese who was listed as dead, a computer hacker named Root who wants access to the Machine, and government officials who want to keep all knowledge of the Machine a complete secret.

Top-lawyer Ron Trott runs his own prestigious L.A. law firm, which offers first-rate criminal defense, charging top-dollar to the wealthy, guilty or innocent or civil party, or occasionally accepts a case for the publicity or for a friend. He has an elaborate team, mainly comprised of specialists, from detectives and ex-public prosecutor Luther Graves to various paralegals such as a specialist in jury-selection and psychology. However Trott has a bright right-hand, charming Tom Nicholson, who is likely to become at least as good a pleader, provided he can control one weakness Ron seems immune for: human feelings such as sympathy, sincere disgust or compassion can cloud the cool competitive killer-instinct to win at any cost to earn a king's ransom.

Overwhelmed by the brutal murder of her mentor and friend, Dr. Ann Coulter, young bioanthropologist Dr. Sloan Parker continues Coulter's secret DNA research at Whitney University in Southern California. Coulter believed global warming spawned a brilliant new species of human that is determined to eliminate Homo sapiens, just as Homo sapiens has, in its perception of manifest destiny, killed off competing species.

In 1989, the Ebola virus appears in chimpanzees in a research lab in the suburbs of Washington, D.C., and there is no known cure; a U.S. Army scientist puts her life on the line to head off an outbreak before it spreads to the human population.

500 feet beneath the ocean's surface, the U.S. ballistic missile submarine Colorado receive their orders. Over a radio channel, designed only to be used if their homeland has been wiped out, they're told to fire nuclear weapons at Pakistan. Captain Marcus Chaplin demands confirmation of the orders only to be unceremoniously relieved of duty by the White House. XO Sam Kendal finds himself suddenly in charge of the submarine and facing the same difficult decision. When he also refuses to fire without confirmation of the orders, the Colorado is targeted, fired upon, and hit. The submarine and its crew find themselves crippled on the ocean floor, declared rogue enemies of their own country. Now, with nowhere left to turn, Chaplin and Kendal take the sub on the run and bring the men and women of the Colorado to an exotic island. Here they will find refuge, romance and a chance at a new life, even as they try to clear their names and get home.