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Leonard Hofstadter and Sheldon Cooper are both brilliant physicists working at Cal Tech in Pasadena, California. They are colleagues, best friends, and roommates, although in all capacities their relationship is always tested primarily by Sheldon's regimented, deeply eccentric, and non-conventional ways. They are also friends with their Cal Tech colleagues mechanical engineer Howard Wolowitz and astrophysicist Rajesh Koothrappali. The foursome spend their time working on their individual work projects, playing video games, watching science-fiction movies, or reading comic books. As they are self-professed nerds, all have little or no luck with women. When Penny, a pretty woman and an aspiring actress from Omaha, moves into the apartment across the hall from Leonard and Sheldon's, Leonard has another aspiration in life, namely to get Penny to be his girlfriend.

Centers on the adventures of a mother and her two adult daughters, both of whom unknowingly are their family's next generation of witches, who lead seemingly quiet, uneventful modern day lives in Long Island's secluded seaside town of North Hampton. When one of the daughters becomes engaged to a young, wealthy newcomer, a series of events forces her mother to admit to her daughters they are, in fact, powerful and immortal witches.

Detective Catherine Chandler (Kristin Kreuk), shaken to the core over the fact that everything she thought she knew about her life has been a lie, is determined to get answers to the secrets that have been revealed about her family. Cat must also try to navigate her evolving relationship with handsome doctor Vincent Keller (Jay Ryan), who struggles with becoming a terrifying beast when he is enraged, unable to control his super-strength and heightened senses. Cat and Vincent continue to grapple with the desire to be a normal couple while trying to keep a low profile in order to stay one step ahead of the mysterious organization known as Muirfield, now on the hunt for both of them.

Young Merlin (Colin Morgan) is a teenager, discovering and then learning to master his magical gift. Magister Gaius (Richard Wilson), King Uther Pendragon's (Anthony Head's) learned court physician to whom he's assigned as humble page, teaches him medicine, coaches his magical self-study, and warns him of Uther's strong aversion to magic. Merlin becomes squire to the noble but imprudent crown Prince, Arthur (Bradley James), whose fate is linked with Merlin.

John Winchester raised his two sons Sam and Dean to hunt and kill all things that go "bump in the night" after his wife Mary was murdered by an evil supernatural being when the boys were little. 22 years later the brothers set out on a journey, fighting evil along the way, to find their recently-missing father; when they finally do he reveals he knows what demon killed their mother and has found a way to track and kill it. Meanwhile, Sam develops frightening abilities such as seeing visions of people dying before it actually happens. These visions are somehow connected to the demon that murdered his mother and its mysterious plans that seem to be all about Sam. When their father dies striking a deal with that very same demon, the brothers determine to finish his crusade. But disturbing revelations about Sam's part in the demon's apocalyptic plan are presented when John's dying last words to Dean are revealed.

Portland detective, Nick Burkhardt, has seen some gruesome crime scenes, but nothing prepares him for the strange visions he begins seeing: seemingly regular people momentarily transforming into hideous monsters. A visit from his only living relative reveals the truth. Nick has inherited the ability to see supernatural creatures, and as a "Grimm," he is tasked with keeping the balance between mankind and the mythological. A reformed "Big Bad Wolf" becomes his greatest (and also reluctant) ally and confidant. It's not long before his work as a policeman leads Nick to the criminals he once thought were only found in fairy tales.

Clary Fray is a normal teenager living in Brooklyn with her mother. One day, she discovers that she is descended from a line of Shadowhunters; humans born with angelic blood that fight to protect our world from demons. After her mother is kidnapped, Clary must team up with three Shadowhunters: Jace, Alec and Isabelle and her best friend Simon on a quest to find her mother and recover her past.

For Emma Swan, life has been anything but a happy ending. But when she's reunited with Henry - the son she gave up for adoption ten years ago - on the night of her 28th birthday, everything changes. The now 10-year-old Henry is in desperate need of Emma's help because he believes from reading a book of fairy-tales that she's the daughter of Snow White and Prince Charming - who sent her away from the Enchanted Forest to be protected from a curse that was enacted by the Evil Queen. Emma initially refuses to believe a word of Henry's story but soon finds that his hometown of Storybrooke, Maine is more than it seems. Because it's in Storybrooke that all of the classic characters we know are frozen in time with no memories of their former selves - except for the Evil Queen, who is Storybrooke's mayor and Henry's adoptive mother Regina Mills. Now, as the epic "Final Battle" for the future of both worlds approaches, Emma will have to accept her destiny and uncover the mystery behind a place where fairy-tales are to be believed.

Lucifer Morningstar, bored from his sulking life in hell, comes to live in Los Angeles. While there, he helps humanity with its miseries through his experience and telepathic abilities to bring people's deepest desires and thoughts out of them. While meeting with a Detective in his nightclub (Lux), a shootout involving him and the Detective leads him to become an LAPD consultant who tries to punish people for their crimes through law and justice.

We're flashing back to 1914, with Kol on a quest to form an alliance with the witches of the French Quarter. Awakening will gives fans answers to some major burning questions about Kol's past, including how and why he found himself up against his siblings, why he was daggered and the unique backstory he has with the New Orleans witches.

The story of several young people from around the world who represent the next stage in human evolution, possessing special powers, including the ability to teleport and communicate with each other telepathically. Together they work to defeat the forces of evil.

When she was a deeply troubled teenager, Nikita was rescued from death row by a secret U.S. agency known only as Division, who faked her execution and told her she was being given a second chance to start a new life and serve her country. What they didn't tell her was that she was being trained as a spy and assassin. Throughout her grueling training at Division, Nikita never lost her humanity, even falling in love with a civilian. When her fiancé was murdered, Nikita realized she had been betrayed and her dreams shattered by the only people she thought she could trust, so she did what no one else before her had been able to do: she escaped. Now, after three years in hiding, Nikita is seeking retribution and making it clear to her former bosses that she will stop at nothing to expose and destroy their covert operation.

After the Battle of New York, the world has changed. It now knows not only about the Avengers, but also the powerful menaces that require those superheroes and more to face them. In response, Phil Coulson of the Strategic Homeland Intervention, Enforcement and Logistics Division assembles an elite covert team to find and deal with these threats wherever they are found. With a world rapidly becoming more bizarre and dangerous than ever before as the supervillains arise, these agents of S.H.I.E.L.D. are ready to take them on.

After centuries of quarreling, Stefan and Damon Salvatore return to their original town of Mystic Fall, Virginia. Stefan, the selfless, brave, guilt-ridden brother, meets a high school girl named Elena Gilbert whom he instantly falls in love with, while Damon, the gorgeous, dangerous and selfish vampire, is after his brother's girl to pay him back for making him turn into a vampire in 1864.

Ichabod Crane is resurrected and pulled two and a half centuries through time to unravel a mystery that dates all the way back to the founding fathers.

16-year-old Cassie moves from California to live with her grandmother in Chance Harbor, Washington, and falls in love with a mysterious boy named Adam. But, when she enrolls in high school there, she realizes that he, she and all the other elite students at the school are witches. She befriends their leader, Diana, but soon discovers that Adam and Diana are dating, which leads to drama.

The series is set 97 years after a devastating nuclear war wiped out almost all life on Earth. The only known survivors are the residents of twelve space stations in Earth's orbit prior to the war. The space stations banded together to form a single massive station named "The Ark", where about 2,400 people live. Resources are scarce and all crimes no matter their nature or severity are punishable by death ("floating") unless the perpetrator is under 18 years of age. After the Ark's life support systems are found to be critically failing, one hundred juvenile prisoners are declared "expendable" and sent to the surface in a last ditch attempt to determine if Earth is habitable again. The teens arrive on a beautiful planet they have only seen from space. Confronting the dangers of this rugged new world, they struggle to form a tentative community. However they discover that not all humanity was wiped out. There are people on Earth who survived the war, called "grounders" by the 100. The Ark consists of the space stations previously representing the nations of the UK, USA, Australia, Canada, China, Japan, India, Russia, Venezuela, France, Brazil, and Uganda.

Barry Allen was struck by lightning and got in a coma for 9 months. After he awoke from his coma 9 months later, Barry met Cisco Ramon, Harrison Wells and Caitlin Snow. He later on realized that he has powers and how it had been caused by the explosion of the particle accelerator.