A young teenage girl escapes her life in Nebraska and her alcoholic parents, taking a pistol along for the ride. Along the way she meets Glenda, who takes her under her wing.

Evelyn Salt is a CIA agent and highly respected by all, including her boss, Ted Winter. Out of the blue, a Russian spy walks into their offices and offers a vital piece of information: the President of Russia will be assassinated during his forthcoming visit to New York City to attend the funeral of the recently deceased U.S. Vice President. The name of the assassin: Evelyn Salt. Concerned about the safety of her husband, who she cannot contact, she goes on the run. Winter refuses to accept that she is a mole or a double agent but her actions begin to raise doubts. Just who is Evelyn Salt and what is she planning?

Rose Hathaway is a dhampir, half-vampire and half-human, who is training to be a guardian at St Vladimir's Academy along with many others like her. There are good and bad vampires in their world: Moroi, who co-exist peacefully among the humans and only take blood from donors, and also possess the ability to control one of the four elements - water, earth, fire or air; and Strigoi, blood-sucking, evil vampires who drink to kill. Rose and other dhampir guardians are trained to protect Moroi and kill Strigoi throughout their education. Along with her best friend, Princess Vasilisa Dragomir, a Moroi and the last of her line, with whom she has a nigh unbreakable bond, Rose must run away from St Vladimir's, in order to protect Lissa from those who wish to harm the princess and use her for their own means.

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