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Dr. Luisa Delgado ran the South Philly Women's Clinic so that poor women could get the medical help they needed. Dr. Dana Stowe did medical research on cancer to help women. Together they now run a women's clinic at Philadelphia's Rittenhouse Hospital to help all women.

Erica Shepherd is a brilliant former CIA operative, now known as the most notorious traitor in American history, serving a life sentence in a Supermax prison. Against every fiber of his being, but with nowhere else to turn, FBI Agent Will Keaton enlists Shepherd to help track down a fiercely dangerous and elusive criminal she knows all too well. For Keaton, it's not easy to trust the woman who cost him so much. While Shepherd and Keaton have different motivations for bringing the enemy to justice, they both know that to catch a spy - they must think like one.

A man comes to terms with a potentially terminal diagnosis.

Follows the lives of five surgeons as they push the limits of their personal and professional feelings.

A relationship forms between a gifted young girl and a man sprung from prison who has been tasked with protecting her from the evil elements that hunt her power.

Jonathan Smith is a probationary angel sent back to Earth to help people. During the series' first episode, he meets embittered ex-policeman Mark Gordon (as Jonathan is walking along a little-used road, on which Mark happens to be driving). Jonathan helps reform Mark, with the grateful Mark agreeing to become Jonathan's right-hand associate in carrying out the heavenly mission. The two begin traveling the country as itinerant workers, receiving assignments from "the Boss" (God), with their mission being to deliver love, understanding and humility to the people they encountered. Typical episodes stressed moral, Christian themes; though many episodes dealt with common human failings, such as egotism, bitterness and greed, some shows addressed such topics as racism and cancer. A few shows, however, were played mainly for laughs (such as Landon recreating his first famous starring role in a takeoff of his 1957 film I Was a Teenage Werewolf and his role in in little house on the prairie).

A former Supreme Court Justice starts his own law firm.

With the subtleness of the invisible and the potential deadliness greater than a bomb, disease can the most dangerous threat of all. When such outbreaks occur, an elite team of medical investigators from the National Institutes of Health lead by Dr. Stephen Connor is on the case to get to the bottom of the danger anywhere in the country. However, the medical situation is only part of the problem as their public relations officer simultaneously attempts to control to prevent public panic and complicate things still more.

Michael Holt is a successful doctor who has a thriving practice. One day he runs into his ex-wife Anna, also a doctor. They spend some time together. He later learns that she died before he met her. He goes to her memorial and learns she was working in an inner-city clinic, and when he goes there, he can't help but assist. Before long, people from the clinic come to see him. He continues to see Anna, who tries to get him to do good. He decides to work at the clinic as well as at his practice.

As a single mother and the Chief Nursing Officer at Richmond Trinity Hospital in Richmond, Virginia, Christina Hawthorne makes care-taking her life's work.

Once a successful and selfish Wall Streeter, Kevin Finn is on a downward spiral as he realizes he hates his life, which led to him trying to commit suicide. To regroup, Kevin heads back to his hometown of Taylor, Texas to live with his straight-laced, recently widowed, aeronautical engineer twin sister Amy Cabrera and her teenaged daughter Reese Cabrera, the latter who is not happy to see her uncle as he did not support them in their time of grief. Shortly after his arrival in Taylor, Kevin discovers from his protector Yvette who no one else can see that he is the only surviving of the thirty-six righteous souls of his generation, something he cannot tell anyone. His God appointed mission under Yvette's protection is to find then anoint the replacement thirty-five, which he is to do by helping others, those specific tasks which he has to listen to the universe which will direct him. The successful completion of each task will result in a vision leading to finding the thirty-five. Kevin's problems are that he may not want to do any of these tasks either in seeming harm to himself, in his own selfishness and in seeing some of those he is directed to help as being even more selfish than him. It is made all the more difficult as some of his actions may seem more than just a little odd to his family and friends, especially to Amy who may believe that Kevin is still suffering from his suicidal tendencies. Through it all, Yvette and her colleagues still have to find out what happened to the original thirty-five and why Kevin was spared.

Three Rivers is about the lives of organ donors, the doctors, and recipients of the organs at Three Rivers, a preeminent transplant hospital in Pittsburgh. Dr. Andy Yablonski is the leader of the team of surgeons: Dr. Miranda Foster, a woman with a reputation of being a rebel and who strives to live up to her father's legacy; Dr. David Lee, the surgeon that breaks all the ladies' hearts; Ryan Abbott, the inexperienced new transplant coordinator with a complex new way of transferring organs to the patients; Dr. Sophia Jordan, the head of organ surgery, and Pam Acosta, Dr. Andy Yablonski's operating assistant and best friend. These are the stories of organ surgeons and what it's like to be in a race against the clock to save lives.

A young Silicon Valley tech-titan enlists a veteran surgeon with a controversial past in starting a hospital with a cutting-edge, new school approach to medicine.

Dr. Sydney Hansen, a successful plastic surgeon in Hollywood, California, quits her private practice and returns to her hometown in Providence, Rhode Island after the sudden death of her controlling, demanding mother Lynda, in order to keep her dysfunctional family together with a little help and advice from Lynda who gives advice from beyond the grave in helping Sydney deal with her new career as a doctor for the local free clinic and dealing with her distracted veterinarian father Jim, her mixed-up sister Joanie, and younger brother Robbie, a small-time hustler.

Jack Killian is an ex-cop in San Francisco. He quit the police force after accidentally shooting his partner. He was approached by Devon King, the manager of a local radio station, and accepted a job as a talk-back host. Ever the humanitarian, Jack (together with his side-kick Billy Po) often gets personally involved with the plight of those who call his show.

A crusty old veteran big-rig trucker teams up with a college-educated youngster to haul cargo across the country.

Jackson Brooks is a successful attorney who seems to have it all. He's engaged to his boss, Marina, and he's on the fast track to becoming partner at his firm, but his world is turned upside down when his long-lost childhood friends unexpectedly reappear after 25 years.

Despite a difference in age, race, culture and lifestyle, the residents of a Manhattan apartment building find that the more their lives intertwine, the more complex and compelling their connections become, thus proving life's challenges are better faced alongside family, even if it's the one you make wherever you find it. All under one roof, we will meet a recovering war vet, a pregnant teenage girl and her single mom, a cop with an unexpected love interest, a woman hiding a terrifying secret from her husband and a millennial lawyer who might find his grandfather is the best and worst roommate he ever could have hoped for.