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A secret government plan to dig up historical figures and clone them has worked. It is 16 years later, and the clones are now in high school. The five main characters are Abe Lincoln, an all around nice but naive guy who lusts after the school sexpot Cleopatra, who is dating the macho JFK. Also, Abe's two best friends are Joan of Arc, an angst ridden goth girl who is in love with him, and Gandhi, a none-stop party animal. Clone High bravely tackles challenging teen issues, such as sleep deprivation, catching ADD from toilet seats, the evils of litter, and having the guy you like not like you back the same way you like him. Will Abe get together with Cleo, or be thwarted by the handsome JFK? Will Joan finally get Abe to notice her? Who's to say?

Steve and Frank Smith are brothers who teach the history department in the worst university in America.

Andy French is an aspiring cartoonist who has trouble holding a job or a girlfriend even while he rooms with two other eccentric roommates in an apartment in the Mission Hill area of the city of Cosmopolis. The fact that he has to house his obnoxiously precocious younger brother, Kevin, is no help. However, this quartet of disparate individuals manages to struggle through life's bizarre trials even as they learn to get along.

Jay Sherman is an overweight and somewhat snobbish New York TV movie critic who is forced to review the most pathetic films to which is he always says, "It stinks." In addition to the film parodies, the show also deals with his professional life working for his tyrannical media mogul boss and his personal life with his friends and family. In a world that seems determined to snub him both in the asinine arts he has to endure and his own difficult relationships, Jay gets along as best he can, while enjoying life's bright spots.

The misadventures of a goofy family deformed by toxic waste.

Xander Crews is a billionaire playboy whose alter ego is the superhero Awesome X. He'd much rather goof around as a superhero than tend to the everyday aspects of running a corporation. The only problem is that Awesome X has gotten rid of every super-villain in the city, and now his board head Stan wants him to retire as a hero and get down to saving the company he's been running into the ground with his superhero expenses. Coincidentally, a new super-villain named Killface appears. His goal is to destroy humanity using the Annihilatrix, a machine which upon completion will hurl the earth into the sun. The only problem is that he has no way of getting the 12 billion dollars needed to complete his doomsday device. Luckily there happens to be a billionaire playboy in town...

In a surreal world, a large maximum security prison, which houses thousands of dangerous inmates is run by an eccentric warden and his equally odd staff.

Orel Puppington is an optimistic, well-intentioned, and devoutly religious 11-year-old whose Christian devotion, enthusiastic church attendance, and general naiveté leads him to grossly misinterpret Bible lessons, often with morbid and ghastly consequences. In doing so, he unintentionally exposes the hypocrisy and duplicity of his family (particularly his father Clay), the members of his community, and ultimately, organized religion itself. Set in the fictional American state of Statesoda, which is located in the middle of the lower 48 states, "Moral Orel" has a stop-motion animation style similar to "Davey & Goliath", and appears to parody the religious undertones of the latter show. However, creator Dino Stamatopoulos intended for the show to be more of a parody of whole 1950's sitcoms such as "Leave It To Beaver" and "Father Knows Best".

Eric Duckman (Jason Alexander) isn't your average suave, sophisticated private eye. In fact, he's rude, ignorant, slovenly, and hasn't had a date in years. With the help of his infinitely more capable sidekick, Cornfed Pig (Gregg Berger), Duckman manages to solve enough cases to cover his alimony payments and cable television bills.

A divorced father, he has custody of his 23-year-old slacker son Ben, who dreams of wealth and freedom but is too lazy to find a real job. Dr. Katz's receptionist is the acerbic Laura. He spends his free time in the bar "Jacky's 33" with his friends Stan and Julie, the bartender.

After mastering immortality, mad scientist Victor Frankenstein turns his attention to time travel, creating a number of wormholes connected to his Eastern European village, allowing him access to any time and place. He uses these portals to conduct more of his scientific experiments.

An anime spoof about a balding boy and his quest to find perfect hair.

Harvey Birdman, the superhero formerly known as Birdman, is now a practicing (and dimwitted) lawyer. His cases always involve legal disputes between cartoon characters. Past cases involve custody of Jonny Quest, a copyright infringement case between the Chan Clan and Jabberjaw, and Fred Flintstone's possible mob connections.

TV series about the life of Brendon Small, an eight-year-old visionary who, using his friends Jason and Melissa as actors, have managed to direct over a thousand homemade films. His parents are divorced, but it doesn't feel strange since so many other kids' parents are divorced. His friend Jason actually feels upset because his parents are still together. At school, he is taught soccer by his coach John McGirk, or as he calls him, "that weird Irish guy".

An all-cynical, all-evil absurdist variety show that parodies the classic educational PBS shows of the 1970s, made up of old cartoons and educational films, children, and puppets from one's worst nightmares.

In the east village, the twentysomething guy, Alex finally moves into this own apartment in New York City's East Village. There he finds that single life is not a walk in the park as he deals with urban life, his boring job at the copy shop, his irritating friends, his selfish sister and his crush on an unattainable goth girl. Yet, for all the troubles, life in the city is still worth it.

"The Brak Show is a story of a neighborhood. It's the story of a family. It's the story of what happens when adults have children and those children go to school. And Brak is in it. He lives in a house. A house on a quiet street not unlike yours or mine. A house in a neighborhood. That's The Brak Show." So goes Cartoon network's description of the new sitcom starring Brak, the absent-minded space pirate from the Space Ghost cartoons. He goes through the all the typical sitcom situations with his friend Zorak. Also along for the ride are Brak's parents, his brother Sisto, and his next-door neighbor Thundercleese.

Take New York City, add every horrifying beast, science-fiction freak, and fantasy faerie, shake thoroughly, and you've got Ugly Americans.