A modern take on the cases of Sherlock Holmes, with the detective now living in New York City.

Lucifer Morningstar, bored from his sulking life in hell, comes to live in Los Angeles. While there, he helps humanity with its miseries through his experience and telepathic abilities to bring people's deepest desires and thoughts out of them. While meeting with a Detective in his nightclub (Lux), a shootout involving him and the Detective leads him to become an LAPD consultant who tries to punish people for their crimes through law and justice.

Captain Ray Holt takes over Brooklyn's 99th precinct, which includes Detective Jake Peralta, a talented but carefree detective who's used to doing whatever he wants. The other employees of the 99th precinct include Detective Amy Santiago, Jake's over achieving and competitive partner; Detective Rosa Diaz, a tough and kept to herself coworker; Detective Charles Boyle, Jake's best friend who also has crush on Rosa; Detective Sergeant Terry Jeffords, who was recently taken off the field after the birth of his twin girls; and Gina Linetti, the precinct's sarcastic administrator.

Since geeky Chuck accidentally became the mental host of the Intersect, an unprecedentedly powerful computer mind containing all information available to the US government, he's a primordial national security asset and risk. So CIA and NSA each appoint a top agent to guard Chuck, and often get involved with him in spy adventures. Meanwhile his identity must be kept secret from Chuck's sister, her perfect partner Devon, both surgeons, and Chuck's goofy colleagues in Buy More, the Burbank electronics store where he works as a cover.

While running from a drug deal gone bad, brilliant young college-dropout Mike Ross slips into a job interview with one of New York City's best legal closers, Harvey Specter. Tired of cookie-cutter law school grads, Harvey takes a gamble by hiring Mike on the spot after recognizing his raw talent and photographic memory. Mike and Harvey are a winning team. Although Mike is a genius, he still has a lot to learn about the law; and while Harvey might seem like an emotionless, cold-blooded shark, Mike's sympathy and concern for their cases and clients will help remind Harvey why he went into law in the first place. Mike's other allies in the office include the firm's best paralegal Rachel and Harvey's no-nonsense assistant Donna. Proving to be an irrepressible duo and invaluable to the practice, Mike and Harvey must keep their secret from everyone including managing partner Jessica and Harvey's arch nemesis Louis, who seems intent on making Mike's life as difficult as possible.

The unlikely partnership between charming con artist Neal Caffrey and straight-man FBI agent Peter Burke. Caffrey provides his expertise to help Burke catch other elusive criminals in exchange for his freedom, and together they prove that to solve the hardest crimes, you must hire the smartest criminal.

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