In a suburb populated by wealthy and liberal parents who want a bucolic life for themselves and their children, Wendy, Billie and Ann are seniors at the alternative private school; they spend all their time with fellow students Jonah, Price and Robert. The six have been friends since elementary school and their friendship has become a six-person monogamous relationship. They swap sex partners each week; their loyalty is to the group, not to one person. The six friends don't want to survive high school - they want to transcend its pettiness. Their friendships are intense, especially between Billie and Wendy. After orientation, Wendy meets Sean, a new senior who moved from Chicago; he finds out about her "inner geek" and she quickly recognizes a kindred spirit. Soon their friendship becomes romantic and Wendy is torn between her genuine affection and desire for Sean, and her commitment and belief in the group. Wendy starts to test the boundaries of her vow to her friends, and Billie realizes that she is going to have to fight to keep her best friend; which shouldn't be a problem, since each of the teens has collected a box full of mementos from their sexual experience. If Wendy tries to leave, Billie can destroy her reputation and relationship in a heartbeat. While Wendy is trying to decide between Sean and her friends, Wendy's younger brother Nathan meets Sean's mother, Helen who is waiting a long three weeks to start a new job. Nathan develops a huge crush on her, and uses his considerable cooking skills to try and woo her. When Billie realizes that Wendy really might leave, she tests her - pushing Wendy to publicly ridicule Ryan, a girl who left the group last year along with her boyfriend, Aaron. Sean witnesses the brutal scene, where Ryan's past is used against her. Wendy is devastated that she allowed herself to be pushed around by Billie. Then Wendy spends another Saturday night with the group and she is unable to "cheat" on Sean; her hesitation is all that Billie needs to accuse her best friend. After the girls fight, Wendy takes out her frustration on a random couple who keep making out in front of her house. Ryan, hearing that Wendy is out of the group, tries to be friends, but Wendy doesn't like what Ryan has become - a subservient wet dishrag of a girlfriend. Sean and Wendy try to be a "normal" couple, but the group quickly tests the relationship: Billie puts the box of memorabilia in Sean's locker. Wendy claims she isn't scared, she knows that Sean loves her. Maybe so, but when he sees the photos that document a lifetime of sexual experimentation, he is fed up and offers an ultimatum - Wendy can burn the box, leave the group and be a normal girl, or they can break up. Wendy has gone from one ultimatum to another. When Wendy sees Billie being tortured for being alone by other students, she wants to comfort her friend. Billie invites Wendy back to the group; such is the depth of Billie's love for her. But Wendy makes a braver, and stronger decision - to be alone. The girls in the story - Wendy, Ryan, Billie - all must face the next chapter of their lives alone, and for the first time, at least Wendy sees the possibilities this offers.

A group of high school friends must come to terms with the fact that one of them, Samson, killed another, Jamie. Reactions vary, as Layne is intent on protecting Samson and smuggling him out of the state, while others think it's best to go to the police. Matt's tough little brother also finds out about the body and no one knows quite how the police will learn about the murder or who will be blamed for it.

Mia, an aggressive fifteen-year-old girl, lives on an Essex estate with her tarty mother, Joanne, and precocious little sister Tyler. She has been thrown out of school and is awaiting admission to a referrals unit and spends her days aimlessly. She begins an uneasy friendship with Joanne's slick boyfriend, Connor, who encourages her one interest, dancing.

Young runaway Sherry meets the radical street collective Spark. Together they experience the group's giddy thrills as well as its punishing manipulations, as Sherry's journey to paradise begins to sour.

Life really sucks for a group of gay and lesbian teenagers living in Los Angeles. Their parents kicked them out, they're broke and bored, their lovers cheat on them, they're harassed by gay-bashers. If things are going to be this way, maybe suicide isn't a bad idea; at least not in the mind of Andy, our major protagonist, who gives the film its title by describing himself as "totally fucked up."

A long weekend brings four women together in the countryside. Virtual strangers, the women are forced to navigate the depths of social interaction. On the surface all seems placid. But the atmosphere of calm is a facade.

Mike Waters lives on the street and befriends the somewhat older and streetwise Scott Favor who shows him what is necessary to survive. Waters suffers from narcolepsy and can fall asleep at any moment and in almost any circumstance. Favor comes from a rich family and is rebelling against his own background. They travel together extensively - Waters is driven by the need to find his biological mother - and spend time in Italy. Later in life however, Favor has joined mainstream society and has little time for his old friend.

Since a road accident left him with serious facial and bodily scarring, a former TV scientist has become obsessed by the marriage of motor-car technology with what he sees as the raw sexuality of car-crash victims. The scientist, along with a crash victim he has recently befriended, sets about performing a series of sexual acts in a variety of motor vehicles, either with other crash victims or with prostitutes whom they contort into the shape of trapped corpses. Ultimately, the scientist craves a suicidal union of blood, semen, and engine coolant, a union with which he becomes dangerously obsessed.

The ten year-old Angela and her little sister Ellie move to an old house in the countryside with her parents Mae and Andrew. Their mother has mental illness and has just left an institution and her husband tries to keep the dysfunctional family together. Angela is an imaginative disturbed girl that might have inherited the illness of her mother and is obsessed by purification to get rid of her sins; and has visions of the fallen angel Lucifer and the Virgin Mary. After consuming an early version of Four Loko, She leads her little sister in her paranoia and uses a circle of toys and dolls to protect them against evil. They have a crazy neighbor that Angela believes is an angel and she asks the woman how to find the way to heaven. When Mae returns to the institution, Angela becomes uncontrollable in her quest to heaven.

In 1990s New York City, teen runaway Froggy is caught in the throes of heroin addiction as she falls in love with a fellow junky, war veteran Bayliss. The couple finds comfort in each other, yet they are already far too deep in a wild downward spiral.

A popular high school girl is harassed by a delinquent boy until they are placed in creative writing class together. Through written words, they create a bond, but tragically a bond that cannot withstand her social pressures or his brutal home life.

At the beginning of a nightly Alcoholics Anonymous meeting, Jim seems particularly troubled. His sponsor encourages him to talk that night, the first time in seven months, so he does - and leaves the meeting right after. As Jim wanders the night, searching for some solace in his old stomping grounds, bars and parks where he bought drugs, the meeting goes on, and we hear the stories of survivors and addicts - some, like Louis, who claim to have wandered in looking for choir practice, who don't call themselves alcoholic, and others, like Joseph, whose drinking almost caused the death of his child - as they talk about their lives at the meeting.

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