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Set in modern times, vampires roam the Earth and are humans' mortal enemies. However, a substitute has been found for human blood, a substitute that vampires can consume with the same effect as human blood. This is True Blood. Now humans and vampires can co-exist in harmony, and even form relationships. But there will always be rogue elements on both sides ready to exploit the uneasy truce.

Centers on the adventures of a mother and her two adult daughters, both of whom unknowingly are their family's next generation of witches, who lead seemingly quiet, uneventful modern day lives in Long Island's secluded seaside town of North Hampton. When one of the daughters becomes engaged to a young, wealthy newcomer, a series of events forces her mother to admit to her daughters they are, in fact, powerful and immortal witches.

Living among the citizens of the infamous New Mexico city of Roswell are some who are not there by choice. They are there to follow a destiny given to them by the members of their dying race, a race that they are someday destined to save. This is the background behind the WB series "Roswell". Max Evans, Isabel Evans and Michael Guerin are teenage humans with extraordinary gifts - gifts that are "not-of-this-earth". They are human/alien hybrids, sent here to complete their destiny. Their counterparts have already perished in a war of attrition, thus one day, they will return to their home planet and save their race. Before a fateful day in 1999, the teens hid their gifts. The event that forever changed their lives was when Max healed Liz Parker (a classmate) after she was fatally shot in the stomach in a dispute between two customers at the restaurant where she waitresses. A close relationship then develops between Max and Liz. Central to the first season were the relationships between the hybrids and their human companions. That focus has shifted during the drama's second season. "Roswell" is now distinctly a science-fiction show built on the relationships between humans and aliens.

People all over the U.S and the world start to realize they have special abilities, like telekinesis, healing abilities, flying powers, time travel, invisibility, and the ability to absorb other's abilities. One man, known as Sylar, wants to gain all the power of these "heroes" so he can be the most powerful and evolved human of all, and stops at nothing to gruesomely kill these people. In order to protect themselves from him, these people must help one another before Sylar can destroy them all, while they each deal with problems of their own.

John Winchester raised his two sons Sam and Dean to hunt and kill all things that go "bump in the night" after his wife Mary was murdered by an evil supernatural being when the boys were little. 22 years later the brothers set out on a journey, fighting evil along the way, to find their recently-missing father; when they finally do he reveals he knows what demon killed their mother and has found a way to track and kill it. Meanwhile, Sam develops frightening abilities such as seeing visions of people dying before it actually happens. These visions are somehow connected to the demon that murdered his mother and its mysterious plans that seem to be all about Sam. When their father dies striking a deal with that very same demon, the brothers determine to finish his crusade. But disturbing revelations about Sam's part in the demon's apocalyptic plan are presented when John's dying last words to Dean are revealed.

Portland detective, Nick Burkhardt, has seen some gruesome crime scenes, but nothing prepares him for the strange visions he begins seeing: seemingly regular people momentarily transforming into hideous monsters. A visit from his only living relative reveals the truth. Nick has inherited the ability to see supernatural creatures, and as a "Grimm," he is tasked with keeping the balance between mankind and the mythological. A reformed "Big Bad Wolf" becomes his greatest (and also reluctant) ally and confidant. It's not long before his work as a policeman leads Nick to the criminals he once thought were only found in fairy tales.

The three Halliwell sisters discover that they are descendents of a line of female witches. Each has a special ability (stopping time, moving objects, seeing the future), and they can also combine their abilities into the "Power of Three" to fight demons, warlocks, and other evils.

For Emma Swan, life has been anything but a happy ending. But when she's reunited with Henry - the son she gave up for adoption ten years ago - on the night of her 28th birthday, everything changes. The now 10-year-old Henry is in desperate need of Emma's help because he believes from reading a book of fairy-tales that she's the daughter of Snow White and Prince Charming - who sent her away from the Enchanted Forest to be protected from a curse that was enacted by the Evil Queen. Emma initially refuses to believe a word of Henry's story but soon finds that his hometown of Storybrooke, Maine is more than it seems. Because it's in Storybrooke that all of the classic characters we know are frozen in time with no memories of their former selves - except for the Evil Queen, who is Storybrooke's mayor and Henry's adoptive mother Regina Mills. Now, as the epic "Final Battle" for the future of both worlds approaches, Emma will have to accept her destiny and uncover the mystery behind a place where fairy-tales are to be believed.

Tru Davies, a medical grad student in Boston whose grant is suddenly pulled out from under her, takes a job at a local morgue. There, she discovers that she has the power to "re-live" the previous day over again to help the people who wrongly ended up dead. She uses this gift not only to save lives, but to help her trouble-plagued family - her older sister Meredith, a lawyer and drug addict in denial; and her younger, irresponsible, slacker, gambling brother Harrison.

Lost Girl focuses on the gorgeous and charismatic Bo, a supernatural being called a succubus who feeds on the energy of humans, sometimes with fatal results. Refusing to embrace her supernatural clan system and its rigid hierarchy, Bo is a renegade who takes up the fight for the underdog while searching for the truth about her own mysterious origins.

Brilliant, but socially inept, forensic anthropologist Dr. Temperence Brennan works at the Jeffersonian Institute in Washington DC. After consulting for him on a FBI case, she is approached by cocky yet charming Former Army Ranger turned Special Agent, Seeley Booth to help the Bureau solve crimes by identifying human remains that are too far gone for standard FBI forensic investigations. Brennan's empirical, literal view of the world causes friction with Booths emotive, instinctive attitude creating a volatile relationship. However as their case load increases the symbiotic partnership produces results and with the support of Brennan's Squint Squad, murderers, past and present should be on the look out.

"In every generation there is a chosen one... she alone will stand against the vampires, the demons and the forces of darkness. She is the slayer." Buffy Summers knows this tale by heart, and no matter how hard she tries to be just a "normal girl", she can not escape from her destiny... Thankfully, she is not alone in her quest to save the world, as she has the help of her friends, the hilarious (and surprisingly quite effective) evil-fighting team called "The Scooby Gang". Together, Buffy & co. will slay their demons, survive one apocalypse after another, attend high school and college... and above all, understand that growing up can truly be Hell sometimes... literally.

Medical student Liv Moore gets invited in a party that turns into a macabre zombie arena. Liv wakes up from the dead and becomes a zombie. To maintain her humanity she must eat human brains so she starts to work in the coroner's officer to access brains. Eating a brain gives her that person's traits and memories, so she helps Detective Clive Babineaux solve the murder as a psychic.

When she left Stonehaven - 'for good this time' - Elena Michaels thought she had left the world of supernatural behind. Until the night she got a mysterious call from her pack leader asking her to come back. So now she is heading back, away from her normal life as a photographer in Toronto and back into the world of werewolves, full of rules about protect the pack and a man she had spent years trying to forget. As if things were not bad enough, Elena also happens to be the only living female werewolf.

Ichabod Crane is resurrected and pulled two and a half centuries through time to unravel a mystery that dates all the way back to the founding fathers.

After a meteor shower bursts from the heavens, raining destruction on the unsuspecting citizens of Smallville, years pass, and the healing process leaves the town's inhabitants with scars and secrets. From the ashes of tragedy, a popular yet awkward teen attempts to decipher the meaning of his life and his clouded past. As he struggles with the transition from boyhood to adulthood, Clark finds that his strength and strange abilities set him uncomfortably apart from his peers.

Over fifty years ago, Mick St. John was turned into a vampire. Now in modern Los Angeles, he is a private eye; working cases that often involve the undead. He uses his supernatural abilities to help mortals in need, a difficult task if he is to keep his own identity a secret. Mick's mentor is Josef, a powerful fellow vampire with many connections. One night, a case leads Mick to reporter Beth Turner, a beautiful human woman he feels bound to protect. But while he struggles with his romantic feelings towards Beth, he meets an enigmatic brunette who looks identical to his ex-wife Coraline --the woman who turned him into a vampire, a woman who was supposed to be dead...

Melinda Gordon inherited her "gift" - the ability to see and talk with the spirits of dead people - from, and was coached in its use by her grandmother. Running an antique store in a small town, newly married to a paramedic, Melinda helps the ghosts wandering around who are trapped between worlds by helping them to resolve unfulfilled aspects of their former life.