A comedy series about a bachelor brother and his newly divorced sister living under one roof again. Together, they coach each other through the crazy world of dating while raising her teenage daughter.

After a family scandal leaves Mel, a local politician, in charge of her niece and nephew, she hires a man named Joe to become the family's male nanny, or "manny".

After his friends all go their separate ways, Joey Tribianni leaves New York for Hollywood to pursue his acting career full time. His sister Gina buys him a nice apartment, and he finds a new roommate in his 20-year old nephew Michael (Gina had him when she was 16), who is literally a rocket scientist. Michael's book smarts and Joey's people smarts allow them to help each other out whenever they can, and make them nice companions.

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