The story centers around a man and a woman, whose fates are intertwined and will change forever. Nelson is an avid advertiser living in San Francisco. One day, during a driving test, he meets Sara, a beautiful but seemingly eccentric woman. But, she is falsely accused of cheating and ends up failing the test because of Nelson. After getting kicked out of the exam, Sara waits for him outside and starts to insult him. However, Nelson ignores her and takes off. Then, she traces him down and shows up at his place. She promises to leave him alone only if he gives her a ride. Later that night, she asks him to live with her throughout November on the promise that his life will change for the better. He turns her down saying that he has a girlfriend. On the first day of November, after being fired and dumped on the very same day, Nelson decides to give it a try and then somehow, agrees to spend the whole month with Sara and finds himself in a desperate love affair that he will remember for the rest of his life.

Nora Wilder is freaking out. Everyone around her is either in a relationship, married, or has children. Nora is in her thirties, alone with job she's outgrown and a mother who constantly reminds her of it all. Not to mention her best friend Audrey's "perfect marriage". But after a series of disastrous dates, Nora unexpectedly meets Julien, a quirky Frenchman who opens her eyes to a lot more than love.

Adam is a 27 year old writer of radio programs and is diagnosed with a rare form of spinal cancer. With the help of his best friend, his mother, and a young therapist at the cancer center, Adam learns what and who the most important things in his life are.

Dean Pereira and Cindy Heller Pereira are a young, working class married couple - Dean currently working as a painter, and Cindy working as a nurse in a medical clinic - with a young daughter named Frankie. Despite their relatively tender ages, they are both ravaged by the life they've eked out together and by the experiences they've had leading into their marriage. Dean, a high school drop out, comes from a broken home, where he never really had a mother figure. He never saw himself getting married or having a family despite falling in love at first sight with Cindy. He doesn't have any professional ambition beyond his current work - which he enjoys since he feels he can knock off a beer at 8 o'clock in the morning without it affecting his work - although Cindy believes he has so much more potential in life. Cindy also comes from a dysfunctional family, with her own mother and father not setting an example of a harmonious married or family life. One of her previous serious relationships was with Bobby Ontario, that relationship which has a profound affect on many aspects of her marriage to Dean. Dean and Cindy head off on an overnight getaway together without Frankie, the getaway which may provide a clearer picture if their marriage can survive its many issues.

Sutter Keely lives in the now. It's a good place for him. A high school senior, charming and self-possessed, he's the life of the party, loves his job at a men's clothing store, and has no plans for the future. A budding alcoholic, he's never far from his supersized, whiskey-fortified thirst-master cup. But after being dumped by his girlfriend, Sutter gets drunk and wakes up on a lawn with Aimee Finecky hovering over him. She's different: the "nice girl" who reads science fiction and doesn't have a boyfriend. While Aimee has dreams of a future, Sutter lives in the impressive delusion of a spectacular now, yet somehow, they're drawn together.

Soon after moving in, Beth, a brainy, beautiful writer damaged from a past relationship encounters Adam, the handsome, but odd, fellow in the downstairs apartment whose awkwardness is perplexing. Beth and Adam's ultimate connection leads to a tricky relationship that exemplifies something universal: truly reaching another person means bravely stretching into uncomfortable territory and the resulting shake-up can be liberating.

Meet the Borgens. William Borgens is an acclaimed author who hasn't written a word since his ex-wife Erica left him 3 years ago for another man. In between spying on Erica and casual romps with his married neighbour Tricia, Bill is dealing with the complexities of raising his teenage children Samantha and Rusty. Samantha is publishing her first novel and is determined to avoid love at all costs - after all she's seen what it has done to her parents. In between hook ups, she meets "nice guy" Lou who will stop at nothing to win her over. Rusty, is an aspiring fantasy writer and Stephen King aficionado, who is on a quest to gain 'life experiences'. He falls for the beautiful, but troubled Kate and gets his first taste of love and a broken heart. A tale of family, love (lost and found), and how endings can make new beginnings. There are no rewrites in life, only second chances.

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