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Helen Harris (Kate Hudson) is living the life she's always dreamed of: her career at a top modelling agency is on the rise; she spends her days at fashion shows and her nights at the city's hottest clubs. But her carefree lifestyle comes to a screeching halt when one phone call changes everything. Helen soon finds herself responsible for her sister's children: fifteen-year-old Audrey (Hayden Panettiere), ten-year-old Henry (Spencer Breslin), and five-year-old Sarah (Abigail Breslin). No one doubts that Helen is the coolest aunt in New York City, but what does this glamor girl know about raising kids? The fun begins as Helen goes through the transformation from super-hip to super-mom, but she quickly finds that dancing at 3a.m. doesn't mix with getting kids to school on time, advice that Helen's older sister, Jenny Portman (Joan Cusack), is only too quick to dish out. Along the way, Helen finds support in the most unusual place, with Dan Parker (John Corbett), the handsome young pastor and principal of the kids' new school, and realizes the choice she has to make is between the life she's always loved and the new loves of her life.

Henry Roth lives in a Hawaiian paradise with the company of endless women with no strings attached. This is until he meets Lucy Whitmore. Both Henry and Lucy enjoy the company of each other and feel the start of a serious relationship occurring. Approaching Lucy the next day, Henry is confused when Lucy fails to recognize him. This is the moment Henry discovers that Lucy actually suffers from short term memory loss and can't remember each individual day. Henry won't let this stop him and is prepared to make her fall in love with him all over again, each and every day.

Two years have passed since Carrie Bradshaw finally bagged John "Mr. Big" Preston, the man she was always meant to be with. Just as her friend Charlotte must deal with her young daughter's "terrible two's", Carrie must deal with her relationship taking a turn for the worse - Big likes to watch old black-and-white movies on TV and eat take-out food, which prevents Carrie from feeling like the free-wheeling party girl she used to be. Meanwhile, Miranda copes with a new boss that can't handle an intelligent, powerful woman, and Samantha works a public relations angle that gets the fashionable foursome an all-expense-paid trip to Abu Dhabi.

A romantically challenged morning show producer is reluctantly embroiled in a series of outrageous tests by her chauvinistic correspondent to prove his theories on relationships and help her find love. His clever ploys, however, lead to an unexpected result.

In Manhattan, the lawyer Liv and the school teacher Emma have been best friends since their childhood. They both are proposed to by their boyfriends on the same day and they plan their wedding parties in Plaza Hotel, using the services of the famous Marion St. Claire. However, due to Marion's secretary's mistake, their weddings are scheduled for the same day. None of them agrees to change the date and they become enemies, trying to sabotage the wedding party of the rival.

Cal (Steve Carell) and Emily (Julianne Moore) have the perfect life together living the American dream... until Emily asks for a divorce. Now Cal, Mr Husband, has to navigate the single scene with a little help from his professional bachelor friend Jacob Palmer (Ryan Gosling). Make that a lot of help...

Carmen Lowell is working on the backstage of a play at Yale. When the lead actress, her friend Julia, invites her to Vermont with her to work on a play with a professional cast, she decides to stay with her friends and her pregnant mother. However, she changes her mind after she finds that her friends will all leave for the summer: Lena Kaligaris will travel to a drawing course, Bridget Vreeland, who is in an existential crisis, missing her mother, will travel to an archaeological dig in Turkey, and Tibby Tomko-Rollins is working in a rental and still editing her documentary. Carmen grows a crush on the lead actor Ian, who convinces her to participate in an audition, and she is then invited by the director Bill Kerr to perform the lead female role. Later she finds the truth about the friendship of Julia. The broken-hearted Lena finds that Kostas has just married, and she dates the model of her drawing class. Bridget finds letters addressed to her from her grandmother that her father has hidden, and decides to visit her, discovering information about her mother. Tibby makes love with her boyfriend Brian McBrian and gets scared of a possible pregnancy. In the end, the girlfriends discover that their friendship is real and amounts to more than just a pair of jeans.

Five couples' intertwined lives are turned upside down by the challenges of impending parenthood. Over the moon about starting a family, TV fitness guru Jules and dance show star Evan find that their high-octane celebrity lives don't stand a chance against the surprise demands of pregnancy. Baby-crazy author and advocate Wendy gets a taste of her own militant mommy advice when pregnancy hormones ravage her body; while Wendy's husband, Gary, struggles not to be outdone by his competitive alpha-Dad, who's expecting twins with his much younger trophy wife, Skyler. Photographer Holly is prepared to travel the globe to adopt a child, but her husband Alex isn't so sure, and tries to quiet his panic by attending a "dudes" support group, where new fathers get to tell it like it really is. And rival food truck chefs Rosie and Marco's surprise hook-up results in an unexpected quandary: what to do when your first child comes before your first date?

One night at a friend's house party, a somewhat confident Dave meets a cool and artistic girl named Aubrey. She helps him with his romantic feelings for Jane. They talk about Dave's feelings, and he believes he should tell Jane how he feels. They soon get interrupted by the cops showing up, but decide to walk home together. As the weekend begins, the new friends start to hang out, as well as discuss their relationship... And their virginity. Dave becomes more and more interested in Aubrey, and she reciprocates. Even though she is involved with Roni (her soon to be ex), she has trouble denying her true feelings for Dave. There is one problem, however, Dave is going off to college in another city. Aubrey still has one year left of high school. Will they be able to handle a long distance relationship? Is their love strong enough? Or will Dave chose Jane, the girl of his dreams instead.

Maggie (Hathaway) is an alluring free spirit who won't let anyone - or anything - tie her down. But she meets her match in Jamie (Gyllenhaal), whose relentless and nearly infallible charm serve him well with the ladies and in the cutthroat world of pharmaceutical sales. Maggie and Jamie's evolving relationship takes them both by surprise, as they find themselves under the influence of the ultimate drug: love.

Holly Kennedy is beautiful, smart and married to the love of her life - a passionate, funny, and impetuous Irishman named Gerry. So when Gerry's life is taken by an illness, it takes the life out of Holly. The only one who can help her is the person who is no longer there. Nobody knows Holly better than Gerry. So it's a good thing he planned ahead. Before he died, Gerry wrote Holly a series of letters that will guide her, not only through her grief, but in rediscovering herself. The first message arrives on Holly's 30th birthday in the form of a cake, and to her utter shock, a tape recording from Gerry, who proceeds to tell her to get out and "celebrate herself". In the weeks and months that follow, more letters from Gerry are delivered in surprising ways, each sending her on a new adventure and each signing off in the same way; P.S. I Love You. Holly's mother and best friends begin to worry that Gerry's letters are keeping Holly tied to the past, but in fact, each letter is pushing her further into a new future. With Gerry's words as her guide, Holly embarks on a journey of rediscovery in a story about marriage, friendship and how a love so strong can turn the finality of death into a new beginning for life.

The needy Gigi Haim is a young woman seeking her prince charming somewhere amongst her unsuccessful dates. After dating estate agent Conor Barry, Gigi anxiously expects to receive a phone call from him. However Conor never calls her. Gigi decides to go to the bar where he frequents to see him, but she meets his friend Alex who works there. They become friends and Alex helps Gigi to interpret the subtle signs given out by her dates.

Leo and Paige are a couple who just got married. After an accident, Paige is left unconscious, and when she awakes she doesn't remember Leo. Her parents, whom she hasn't seen since she and Leo got together, come and visit her. She can't believe that she hasn't seen them for such a long time. Leo wants to bring her home with him but her parents want her to go with them. She goes with Leo but when she doesn't recognize anything, she goes to her parents. And she wonders why did she cut off contact with her family. She also runs into her ex and wonders why they broke up. Leo tries to win her back by courting her again.

Rachel is a lawyer. When she was in law school she fell for another student, Dex, who comes from an affluent family, but she was too shy to say anything. When Dex meets her best friend Darcy, who sometimes treats her like dirt, Darcy makes a move on Dex and gets him. Eventually, they get engaged and Darcy asks Rachel to be her Maid of Honor. However, Rachel still has feelings for Dex and still can't say anything. Darcy throws her a birthday party and Dex is there. When she and Dex are alone she blurts out that she had a thing for him in college which surprised him, and after drinking a little they spend the night together. They try to forget the whole thing and agree that it means nothing. Ethan, Rachel's close friend, tells her that she'll spend her entire life regretting that if she does nothing.

After moving in together in an impossibly beautiful New York apartment, Carrie Bradshaw and Mr. Big make a rather arbitrary decision to get married. The wedding itself proves to be anything but a hasty affair--the guest list quickly blooms from 75 to 200 guests, and Carrie's simple, label-less wedding gown gives way to an enormous creation that makes her look like a gigantic cream puff. An upcoming photo spread in Vogue puts the event--which will take place at the New York Public Library--squarely in the public eye. Meanwhile, Carrie's girlfriends--Samantha, the sexpot; Charlotte, the sweet naïf; and Miranda, the rigid perfectionist--could not be happier. At least, they couldn't be happier for Carrie. Charlotte still has the unrealized hope of getting pregnant. Samantha is finding a loving, committed relationship more grueling than she could have imagined. Miranda unwittingly lets her own unhappiness--created when Steve admits to cheating on her just once--spoil Carrie's. After a heated encounter with Steve, she happens to spot Mr. Big and tells him he's crazy to get married. She's really only thinking of her own marriage. But her angry remark gets Mr. Big to thinking.

For three years, Andrew Paxton has slaved as the assistant to Margaret Tate, hard-driving editor at a New York publisher. When Margaret, a Canadian, faces deportation for an expired visa, she hatches a scheme to marry Andrew - he agrees if she'll promise a promotion. A skeptical INS agent vows to test the couple about each other the next Monday. Andrew had plans to fly home that weekend for his grandma's 90th, so Margaret goes with him - to Sitka, Alaska - where mom, dad, and grams await. Family dynamics take over: tensions between dad and Andrew, an ex-girlfriend, Andrew's dislike of Margaret, and her past color the next few days, with the INS ready to charge Andrew with fraud.

Jamie Rellis (

After discovering her boyfriend is married, Carly Whitten tries to get her ruined life back on track. But when she accidentally meets the wife he's been cheating on, she realizes they have much in common, and her sworn enemy becomes her greatest friend. When yet another affair is discovered, all three women team up to plot mutual revenge on their cheating, lying, three-timing SOB.