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Four childhood friends, now in their thirties, are having a reunion. Their lives have gone separate and very different ways. Together again they reminisce about their younger years, especially the eventful period when they were 12 years old.

Chicago Sun Times copy editor Josie Gellar (25), who was desperate to graduate from perfectionist copy editor to reporter, gets her chance when the goody owner orders the editor to cover the high-school scene by undercover. Josie, who was a frustrated, ridiculed nerd, gets a popular make-over from her drop-out, naturally funny brother Rob Geller. Both siblings find love and joys of youth again. But in Josie's case, it's sensitive bachelor teacher Sam Coulson, who enjoys sophisticated conversation. As the publication deadline approaches, the price of blowing their cover seems ever more daunting, yet inevitable unless she sacrifices her career.

Kate (Brittany Snow) is the new girl in school. She catches John Tucker (Jesse Metcalfe) dating three different girls at once: Carrie - the smart girl, Heather - the cheerleader, and Beth - the activist slut; none of them are aware that they are not the only girl in John's heart. Kate, having been raised by a single mother, has seen the pain caused by playboys like John Tucker, and she won't stand idly by. Together with the three jilted ex-girlfriends, they hatch a plan to teach John a lesson. Things rarely go as planned, especially when Kate starts to think that she might be falling for John herself.

Kathryn Merteuil and Sebastian Valmont are seductive, manipulative step-siblings who get what they want when they want it. Kathryn makes a bet with Sebastian: Sebastian must bed Annette, daughter of the headmaster at their school, before the end of summer break. Annette has stated that she would wait until love and marriage to sleep with a man. If Kathryn wins, she gets Sebastian's vintage 1959 Jaguar Roadster. If Sebastian wins, he gets Kathryn, the only girl he knows he'll never have. Also in play is Cecile, a naïve girl whose mother had enlisted Kathryn to help her fit in at her new school. However, Kathryn (with Sebastian's help) plans to ruin Cecile's reputation as revenge on Kat's ex-boyfriend, who left her for Cecile.

The movie is based on the young adult book, The Sisterhood of the Traveling Pants, by Anne Brashares. As four best friends spend their first summer apart from one another, they share a magical pair of jeans. Despite being of various shapes and sizes, each one of them fits perfectly into the pants. To keep in touch they pass these pants to each other as well as the adventures they are going through while apart.

Cher, a high school student in Beverly Hills, must survive the ups and downs of adolescent life. Her external demeanor at first seems superficial, but rather it hides her wit, charm, and intelligence which help her to deal with relationships, friends, family, school, and the all-important teenage social life.

Carmen Lowell is working on the backstage of a play at Yale. When the lead actress, her friend Julia, invites her to Vermont with her to work on a play with a professional cast, she decides to stay with her friends and her pregnant mother. However, she changes her mind after she finds that her friends will all leave for the summer: Lena Kaligaris will travel to a drawing course, Bridget Vreeland, who is in an existential crisis, missing her mother, will travel to an archaeological dig in Turkey, and Tibby Tomko-Rollins is working in a rental and still editing her documentary. Carmen grows a crush on the lead actor Ian, who convinces her to participate in an audition, and she is then invited by the director Bill Kerr to perform the lead female role. Later she finds the truth about the friendship of Julia. The broken-hearted Lena finds that Kostas has just married, and she dates the model of her drawing class. Bridget finds letters addressed to her from her grandmother that her father has hidden, and decides to visit her, discovering information about her mother. Tibby makes love with her boyfriend Brian McBrian and gets scared of a possible pregnancy. In the end, the girlfriends discover that their friendship is real and amounts to more than just a pair of jeans.

Ronald Miller is tired of being a nerd, and makes a deal with one of the most popular girls in school to help him break into the "cool" clique. He offers her a thousand dollars to pretend to be his girlfriend for a month. It succeeds, but he soon learns that the price of popularity may be higher than he expected.

One night at a friend's house party, a somewhat confident Dave meets a cool and artistic girl named Aubrey. She helps him with his romantic feelings for Jane. They talk about Dave's feelings, and he believes he should tell Jane how he feels. They soon get interrupted by the cops showing up, but decide to walk home together. As the weekend begins, the new friends start to hang out, as well as discuss their relationship... And their virginity. Dave becomes more and more interested in Aubrey, and she reciprocates. Even though she is involved with Roni (her soon to be ex), she has trouble denying her true feelings for Dave. There is one problem, however, Dave is going off to college in another city. Aubrey still has one year left of high school. Will they be able to handle a long distance relationship? Is their love strong enough? Or will Dave chose Jane, the girl of his dreams instead.

A comedic story of the search for identity and the redemptive power of unexpected friendship. Danielle is the dirty girl of Norman High School. When Danielle's misbehavior gets her banished to special ed, she teams up with an innocent closet-case and together they head out on a road trip to discover each other and themselves through a funny and serendipitous friendship.

Nicole (Melissa Joan Hart) and Chase (Adrian Grenier) are neighbors but are from two very different worlds. Despite their differences their love lives have a common theme. Their most recent plans for love have fallen through putting them both in a desperate state to fix them. Both Nicole and Chase conspire to pretend to find a romantic interest in each other, with the hopes of attracting the "ones who got away" from them. Leading up to the big school dance, Chase and Nicole find that their scam worked out better than they had planned.

Although cheerful, friendly, intelligent, well-dressed, authentic and wealthy, Charlie Bartlett has problems. With his father gone and his mother loopy and clueless, he's been expelled from every private school for his victimless crimes. Now he's in a public school getting punched out daily by the school thug. He ever longs to be popular - the go-to guy - and the true crux of his troubles is that he invariably finds the means to this end, whatever that might be. At Western Summit High, he makes peace with his tormentor by going into business with him - listening to kids' problems and selling them prescription drugs. Charlie's a hit, but attraction to Susan (daughter of the school's laissez-faire principal), new security cameras on campus, a student's overdose, and Charlie's open world view all converge to get him in serious trouble. Can this self-made physician possibly heal himself and just be a kid?

After a little white lie about losing her virginity gets out, a clean cut high school girl sees her life paralleling Hester Prynne's in "The Scarlet Letter," which she is currently studying in school - until she decides to use the rumor mill to advance her social and financial standing.

Craig is a high-school junior in the gifted program, infatuated with his best friend's girl. When he realizes he's suicidal, he checks himself into the psychiatric ward of a hospital, thinking they'll do an observation, help him, and send him home in time for school the next day. Once in, however, he must stay for a week; the juvenile ward is being renovated, so he's in with adults as well as a few youths. Bobby, a man with a young daughter, shows him around; Craig notices Noelle, about his age. He tries to keep his friends from finding out where he is. He draws, goes to therapy, sings, helps Bobby rehearse an interview. Is this the stuff of insight?

Halley is a young high school student who is disillusioned with love after seeing the many dysfunctional relationships around her. Her parents are now divorced and her father has a new young girlfriend she doesn't care for too much. Her mother is now always alone; and her sister is so overwhelmed by her upcoming wedding that she barely leaves the house anymore. On top of that, the shallowness of all the girls and guys at her school convinces Halley that finding true love is impossible. A tragic accident, however, leads her to meeting Macon, and suddenly Halley finds that true love can occur under unusual circumstances.

After her mother, Karen (Melissa Leo) gets married for the third time, 17-year-old Greta (Hillary Duff), who had witnessed her father kill himself, withdraws within herself, and turns rebellious. In lieu of boot camp she is sent to live with her maternal grandparents, Katherine (Ellen Burstyn) and Joseph (Michael Murphy) where she makes it known that she is determined to kill herself. She then falls for a cook, Julie (Evan Ross) at the local restaurant, much to the chagrin of her grandparents - especially when they find out he had been interned in a juvenile correctional facility. Faced with all-round opposition and unhappy with her life Greta plans her suicide during a boating trip - a plan that will not only expose closeted skeletons, but also shatter and change everyone's lives forever.

In New York City, Molly Gunn is a spoiled, wealthy, immature young woman who lives as if she were a fairytale princess. Her father, a popular rock guitarist, died in a plane crash with her mother when she was little. In a nightclub on her birthday she meets Lorraine "Ray" Schleine, a nasty young girl with an adult attitude, who lives with her careless mother and a terminally-ill father in a fancy uptown apartment. When Molly's accountant vanishes with her US$ 100,000,000.00 inheritance, she is left with nothing but debts and must work to survive--with no previous experience or marketable skills. She is hired to be Ray's babysitter, and their close contact makes Molly reach maturity and Ray act like the 8-year-old she is.

Brandy Klark (