In honor of his late wife who died in a flaming car accident, scientist, Dr. Robert Ledgard, is trying to synthesize the perfect skin which can withstand burns, cuts or any other kind of damage. As he gets closer to perfecting this skin on his flawless patient, the scientific community starts growing skeptical and his past is revealed that shows how his patient is closely linked to tragic events he would like to forget.

Mikael Blomkvist is a disgraced journalist who is asked by a wealthy industrialist to write a biography on his family. But what he really wants Blomkvist to do is to find out what happened to his niece, who went missing 40 years ago. Blomkvist, at first, is not interested, till the man offers to help him clear his name. Blomkvist, begins by talking to the man's relatives who were there when the girl went missing. And some of them are not forth coming. Blomkvist eventually believes that her disappearance might have something to do with some serial killings that took place 20 years before she disappeared. So he asks for a research assistant. So the industrialist's man suggests Lisbeth Salander, a talented hacker who does background checks for them and who even did one on Blomkvist. When he sees her report, he's impressed and asks her to work with him and she does. She's anti-social but is extremely efficient.

Nina (Portman) is a ballerina in a New York City ballet company whose life, like all those in her profession, is completely consumed with dance. She lives with her obsessive former ballerina mother Erica (Hershey) who exerts a suffocating control over her. When artistic director Thomas Leroy (Cassel) decides to replace prima ballerina Beth MacIntyre (Ryder) for the opening production of their new season, Swan Lake, Nina is his first choice. But Nina has competition: a new dancer, Lily (Kunis), who impresses Leroy as well. Swan Lake requires a dancer who can play both the White Swan with innocence and grace, and the Black Swan, who represents guile and sensuality. Nina fits the White Swan role perfectly but Lily is the personification of the Black Swan. As the two young dancers expand their rivalry into a twisted friendship, Nina begins to get more in touch with her dark side - a recklessness that threatens to destroy her.

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