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The 47th ceremony of the People's Choice Awards was held on December 7, 2021, at the Barker Hangar in Santa Monica, California. Hosted by Kenan Thompson, the show was the first to be presented before an in-person audience since 2019. The television broadcast marked the first time the show was aired live simultaneously on both NBC and E! after airing solely on E! for the past three years, and on CBS prior to that.

In October, over 300 nominees spanning 40 entertainment categories across film, television, music, and pop culture were announced. F9: The Fast Saga and This Is Us were the most-nominated entries in the Film and Television categories respectively with eight and six nominations each. Justin Bieber led the Music nominations with 10 to his name. The most-awarded nominees of the night were BTS and Dwayne Johnson, who won three awards each: the former won Group, Song, and Music Video of 2021, while the latter won Male and Comedy Movie Star, and was additionally honored with the People's Champion Award, one of three Icon awards given on the night. Black Widow won Movie of 2021, while Loki won TV Show of 2021. Christina Aguilera was honored with the show's first-ever Music Icon Award, in recognition of her career and contributions to the music industry.