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Leigh Marine Occhi (August 21, 1979—disappeared August 27, 1992) is an American teenager who vanished under mysterious circumstances at her home in Tupelo, Mississippi during Hurricane Andrew. Her mother, Vickie Felton, returned home on the morning of August 27, 1992, to find Occhi missing and evidence of blood in the house.

Searches in and around Tupelo proved fruitless. On September 9, 1992, Occhi's eyeglasses were mailed to her home in an envelope, addressed to her ex-stepfather; law enforcement deemed this action a ruse to distract detectives in their search efforts. In November 1993, a human skull discovered in a soybean field was erroneously attributed to Occhi, but this link was later retracted and the skull was positively identified as that of an adult woman who had gone missing in an adjacent town.