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Timothy McSweeney's Quarterly Concern is an American literary journal, typically containing short stories, reportage, and illustrations. Some issues also include poetry, comic strips, and novellas. The Quarterly Concern is published by McSweeney's. The journal is notable in that it has no fixed format, and changes its publishing style from issue to issue, unlike more conventional journals and magazines. The Quarterly was first published in 1998, and it is edited by Dave Eggers.

The first issue featured only works that had been rejected by other publications, but the journal has since begun publishing pieces written with McSweeney's in mind. The journal is based in San Francisco.