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Blue Murder is a British crime drama television series based in Manchester, originally broadcast on ITV from 2003 until 2009, starring Caroline Quentin as DCI Janine Lewis and Ian Kelsey as DI Richard Mayne. Five series of the programme were broadcast over the course of six years. Reruns have aired on ITV3.

Blue Murder centres on a single mother of four, DCI Janine Lewis (Caroline Quentin), trying to balance a demanding career with raising her young family, whilst constantly battling with her former husband, who has since started a new family of his own.

The series was created by Cath Staincliffe, a novelist and radio playwright. Staincliffe pitched the idea for Blue Murder to ITV and a two-part first series was commissioned by the network. The first series began broadcasting on 18 May 2003. Due to strong ratings, a second series of four episodes was subsequently commissioned and began broadcasting in 2004. Staincliffe was principal writer for the first two series, with John Fay, Jeff Povey and Matthew Hall also contributing scripts for the second series.