James Myers Thompson (September 27, 1906 – April 7, 1977) was an American prose writer and screenwriter, known for his hardboiled crime fiction.

Thompson wrote more than thirty novels, the majority of which were original paperback publications, published from the late-1940s through mid-1950s. Despite some positive critical notice—notably by Anthony Boucher in The New York Times—he was little-recognized in his lifetime. Only after death did Thompson's literary stature grow. In the late 1980s, several of his novels were re-published in the Black Lizard series of re-discovered crime fiction.

His best-regarded works include The Killer Inside Me, Savage Night, A Hell of a Woman and Pop. 1280. In these works, Thompson turned the derided crime genre into literature and art, featuring unreliable narrators, odd structure, and the quasi-surrealistic inner narratives of the last thoughts of his dying or dead characters. A number of Thompson's books were adapted as popular films, including The Getaway and The Grifters.

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