Rosie (Michelle Pfeiffer), a 40-year-old divorced mother produces the has-been television comedy "You Go Girl," which seems doomed since her boss no longer allows the show to tackle any vaguely-controversial subjects. Then she meets Adam (Paul Rudd) , an attractive, spontaneously funny, single, 29-year-old actor at an audition. She successfully casts him, which revives the show's ratings. She also dates him, but her pathological insecurity, focused on their age difference, compromises the relationship. That culminates when she suspects him of infidelity with the show's star, and the studio gives those two their own sitcom.

Fed up with her small-town Bay City existence, Adele August leaves her family and second husband and heads for Beverley Hills with her daughter. The teenager resents the move and her mother's always flamboyant behaviour and in turns plans to get away to university on the east coast. Mum's plans are different - she wants a movie star for a daughter.

Seventeen year old Jason Slocumb, Jr. - Igby to most that know him - comes from east coast old money, the second son of self-absorbed and controlling Mimi Slocumb and medically-diagnosed schizophrenic Jason Slocum, Sr., the latter who has for several years been institutionalized in a Maryland psychiatric facility. While Igby's economics-studying Columbia-attending older brother Ollie Slocum has embraced and aspires to continue their wealthy life, Igby has rebelled against it, considering his brother a fascist (although he could soften that label to Republican). Because of Jason's situation, Mimi has largely left the role of male role model for Ollie and Igby to their godfather, D.H. Banes. Igby's rebellion has led to him being kicked out of one prep school after another, the latest, a military academy, from which Igby escapes before he can graduate. As such, Mimi and D.H. arrange for Igby to live in New York with Ollie for the summer while working for D.H. renovating some of his properties, before Mimi arranges for yet another strict school for the fall so that Igby can at least graduate. Igby is largely able to hide out for most of the summer with the help of Rachel, D.H.'s younger heroin addict mistress, and Sookie, a slightly older waitress with who he falls in love. An issue with Sookie and the aftermath of a joint mission with Ollie leads to Igby having a clearer picture of what his immediate future will look like.

On the Wall Street of the 1980s, Bud Fox is a stockbroker full of ambition, doing whatever he can to make his way to the top. Admiring the power of the unsparing corporate raider Gordon Gekko, Fox entices Gekko into mentoring him by providing insider trading. As Fox becomes embroiled in greed and underhanded schemes, his decisions eventually threaten the livelihood of his scrupulous father. Faced with this dilemma, Fox questions his loyalties.

Anna and Ben, the two children of Jackie and Luke, must cope with the fact that their parents divorced and their father is now with successful photographer Isabel. She does her best to treat the kids in a way that makes them still feel at home when they're with their dad, but she also loves her work and doesn't plan to give it up. But full-time mother Jackie finds Isabel's efforts offensively insufficient and can't understand that work can be important to her as well as the kids. The conflict between them is deepened by the sudden diagnosis of cancer, which might be deadly for Jackie. They all have to learn a little in order to grow together.

After their father passes away, four grown siblings, bruised and banged up by their respective adult lives, are forced to return to their childhood home and live under the same roof together for a week, along with their over-sharing mother and an assortment of spouses, exes and might-have-beens. Confronting their history and the frayed states of their relationships among the people who know and love them best, they ultimately reconnect in hysterical and emotionally affecting ways amid the chaos, humor, heartache and redemption that only families can provide-driving us insane even as they remind us of our truest, and often best, selves.

Everett Stone, who made it on Wall Street, returns home for Christmas with his new girlfriend, Meredith Morton. His ultra-liberal, anti-conventional rustic Connecticut family doesn't exactly warm to the outsider, who despite her best efforts to please the prospective in-laws, looks, sounds, and acts like the conservative bigots they hate, while various Stones have their own problems. Only matriarch Sibyl Stone's unshakable maverick other son Ben gives her a chance, and as Everett won't actively turn against either, she feels more supported by him and a weird romance blossoms. Feeling beleaguered, Meredith calls in help from her easygoing sister Julie, who proves no help to her but soon develops a chemistry with Everett, so everything may now shift if they dare follow their hearts.

Three grown prodigies, all with a unique genius of some kind, and their mother are staying at the family household. Their father, Royal had left them long ago, and comes back to make things right with his family.

A sharp-witted suburban wife, Terry Wolfmeyer, is left to raise her four headstrong daughters when her husband unexpectedly disappears. Things get even more hectic when she falls for her neighbor Denny, a once-great baseball star turned radio d.j. This leaves her daughters out on a limb. They are forced to juggle their mom's romantic dilemmas as well as their own.

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