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The Big Sick is a 2017 American biographical romantic comedy directed by Michael Showalter and written by Emily V. Gordon and Kumail Nanjiani. It stars Nanjiani, Zoe Kazan, Holly Hunter, Ray Romano, Adeel Akhtar and Anupam Kher. Loosely based on the real-life romance between Nanjiani and Gordon, it follows an interracial couple who must deal with cultural differences after Emily (played by Kazan in the film) becomes ill.

The film had its world premiere at the Sundance Film Festival on January 20, 2017. It began a limited theatrical release on June 23, 2017, by Amazon Studios and Lionsgate, before going wide on July 14, 2017. It became one of the most acclaimed films of 2017 and was chosen by American Film Institute as one of the top 10 films of the year. With a budget of $5 million, it grossed over $55 million worldwide, becoming one of the highest-grossing independent films of 2017.

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